Evidence for decidual modulation of contractile function in the pregnant rat uterus

Snyder, Seth W.; Sl, Rigby; Hr, Adams

doi:10.1016/0024-3205(94)00651-2

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2005

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“…Decidual OT may also be acting locally to regulate prostaglandin formation for subsequent actions on the myometrium or it may control hormone secretion, possibly via modulation of I Ca(T) rather than any direct actions on myometrial contractility. Indeed, it has been demonstrated in vitro that incubation of rat myometrial strips with or without decidua modifies the pattern of contractility such that, in the presence of decidua, OT and prostaglandin-induced contractions had a much reduced frequency (30), suggesting paracrine regulation via other decidua-derived mediators.…”

Section: Discussionmentioning

confidence: 99%