Evidence for peptidergic innervation of the endocrine optic gland inSepia by neurons showing FMRFamide-like immunoreactivity

Gall, S. Le; Féral, Colette; Minnen, Jan van; Marchand, Claude-Roland

doi:10.1016/0006-8993(88)90588-4

Cited by 36 publications

(20 citation statements)

References 18 publications

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“…To date, only a few studies concerning the central distribution of neuropeptides have been conducted in the cuttlefish (Le Gall et al 1988;Di Cosmo et al 2000, 2004Di Cristo et al 2007;Boyer et al 2007). The present study describes, for the first time, the distribution of OT-like and VP-like immunoreactivities in the CNS of a decapod cephalopod mollusc, Sepia officinalis, thus extending our knowledge of neuropeptides in the cuttlefish and in cephalopods in general (Feldman 1986;Le Gall et al 1988;Uemura et al 1987;Cornwell et al 1993;Messenger 1996;Di Cosmo and Di Cristo 1998;Di Cosmo et al 2000, 2004Suzuki et al 2000Suzuki et al , 2002Suzuki et al , 2003Takuwa-Kuroda et al 2003;Iwakoshi-Ukena et al 2002, 2004Springer et al 2004;Di Cristo et al 2005Kanda and Minakata 2006;Boyer et al 2007).…”

Section: Discussionmentioning

confidence: 99%

Distribution of oxytocin-like and vasopressin-like immunoreactivities within the central nervous system of the cuttlefish, Sepia officinalis

et al. 2009

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We have investigated the distribution of oxytocin/vasopressin (OT/VP) superfamily peptides in the central nervous system (CNS) of the cuttlefish, Sepia officinalis, by using antibodies raised against mammalian OT and VP. Several populations of OT-like and VP-like immunoreactive cell bodies and fibers were widely distributed in cerebral structures involved in learning processes (vertical lobe complex, optic lobes), behavioral communication (peduncle, lateral basal and chromatophore lobes), feeding behavior (inferior frontal, brachial and buccal lobes), sexual activity (dorsal basal, subpedunculate, olfactory lobes), and metabolism (visceral lobes). The two most remarkable findings of this study were the occurrence of OT-like immunoreactivity in many amacrine cells of the vertical lobe and the dense accumulation of VP-like immunoreactive cell bodies in the subpedunculate 1 lobe. No double-immunolabeled cell bodies or fibers were found in any lobes of the CNS, indicating, for the first time in a decapod cephalopod mollusc, the existence of distinct oxytocinergic-like and vasopressinergic-like systems. The widespread distribution of the immunoreactive neurons suggests that these OT-like and VP-like peptides act as neurotransmitters or neuromodulators.

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Section: Discussionmentioning

confidence: 99%

Distribution of oxytocin-like and vasopressin-like immunoreactivities within the central nervous system of the cuttlefish, Sepia officinalis

et al. 2009

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“…Many FMRF-IR neurons from the subpedunculate area (dorsal basal and subpedunculate lobes) of the brain project to the optic gland, where they form axo-axonal synapses with fibers immunoreactive for GnRH (Di Cosmo and Di Cristo 1998). FMRFamide-like substances inhibit the secretory activity of the optic gland in Sepia (Le Gall et al 1988). Therefore, FMRFamide, together with NPY-like substance(s), may indirectly control the secretory function of the optic gland through GnRH fibers.…”

Section: Discussionmentioning

confidence: 99%

“…Commissural fibers of the optic lobe, peduncle lobe, and olfactory lobe, contralateral connections, and intra-central brain connections are omitted. The diagram is based on descriptions by Young (1962bYoung ( , 1991, Lund (1966), Messenger (1967), Saidel (1979Saidel ( , 1982, Le Gall et al (1988), and Di Cosmo and Di Cristo (1998) …”

Section: Figmentioning

confidence: 99%

Neuropeptide Y-immunoreactive neuronal system and colocalization with FMRFamide in the optic lobe and peduncle complex of the octopus (Octopus vulgaris)

et al. 2001

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The distribution of neuropeptide Y (NPY)-like immunoreactivity and its colocalization with FMRFamide were investigated in the optic lobe and peduncle complex of the octopus ( Octopus vulgaris) by using immunohistochemical techniques. In the optic lobe cortex, NPY-immunoreactive (NPY-IR) fibers were observed in the plexiform layer, although no NPY-IR somata were observed in the outer or inner granular cell layers. In the optic lobe medulla, NPY-IR somata were seen in the cell islands, and abundant NPY-IR varicose fibers were observed in the neuropil. Most of the NPY-IR structures in the medulla showed FMRFamide-like immunoreactivity. In the peduncle lobe, abundant NPY-IR and FMRFamide-IR (NPY/FMRF-IR) varicose fibers were seen in the basal zone neuropil of the peduncle lobe. In the olfactory lobe, NPY/FMRF-IR varicose fibers were also abundant in the neuropil of the three lobules. NPY/FMRF-IR somata, with processes running to various neuropils, were scattered in the median and posterior lobules. In the optic gland, many NPY/FMRF-IR varicose fibers formed a honeycomb pattern. These observations suggest that NPY/FMRF-IR neurons in the optic lobes participate in the modulation of visual information and that those in the optic gland are involved in the regulation of endocrine function.

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“…Eight and seven RFamide-like peptides were identified in the eyestalk of M. rosenbergii and P. monodon, respectively (Sithigorngul et al 1998(Sithigorngul et al , 2001(Sithigorngul et al , 2002b, although FMRFamide was not present. One or more of these related peptides may act to control neurosecretory cells of the eyestalk, as an inhibitory effect of FMRFamide was revealed at the optic gland of Sepia (Le Gall et al 1988). There is also evidence that the inhibitory action of FMRFamide could be counterbalanced by the action of a GnRH-like molecule that can positively stimulate the optic gland of Sepia officinalis (Di Cristo et al 2009).…”

Section: Discussionmentioning

confidence: 99%

“…More recently, the presence of a GnRH-like molecule was found in the thoracic ganglia of M. rosenbergii using anti-octGnRH (Ngernsoungnern et al 2008). It is possible that the RFamide-like peptide in M. rosenbergii may be a local inhibitory signal for neurosecretion while other peptides may act as stimulatory signal for GnRH neurosecretory cells within the ganglia (Le Gall et al 1988;Di Cristo et al 2009). Further investigations employing co-localization of the RF-like molecule with GnRH would be needed to validate this hypothesis.…”

Section: Discussionmentioning

confidence: 99%

The distribution of APGWamide and RFamides in the central nervous system and ovary of the giant freshwater prawn, Macrobrachium rosenbergii

et al. 2011

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Immunohistochemistry was used to identify the distribution of both APGWamide-like and RFamide-like peptides in the central nervous system (CNS) and ovary of the mature female giant freshwater prawn, Macrobrachium rosenbergii. APGWamide-like immunoreactivity (ALP-ir) was found only within the sinus gland (SG) of the eyestalk, in small- and medium-sized neurons of cluster 4, as well as their varicosed axons. RFamide-like immunoreactivity (RF-ir) was detected in neurons of all neuronal clusters of the eyestalk and CNS, except clusters 1 and 5 of the eyestalk, and dorsal clusters of the subesophageal, thoracic, and abdominal ganglia. The RF-ir was also found in all neuropils of the CNS and SG, except the lamina ganglionaris. These immunohistochemical locations of the APGWamide-like and RF-like peptides in the eyestalk indicate that these neuropeptides could modulate the release of the neurohormones in the sinus gland. The presence of RFamide-like peptides in the thoracic and abdominal ganglia suggests that it may act as a neurotransmitter which controls muscular contractions. In the ovary, RF-ir was found predominantly in late previtellogenic and early vitellogenic oocytes, and to a lesser degree in late vitellogenic oocytes. These RFs may be involved with oocyte development, but may also act with other neurohormones and/or neurotransmitters within the oocyte in an autocrine or paracrine manner.

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Evidence for peptidergic innervation of the endocrine optic gland inSepia by neurons showing FMRFamide-like immunoreactivity

Cited by 36 publications

References 18 publications

Distribution of oxytocin-like and vasopressin-like immunoreactivities within the central nervous system of the cuttlefish, Sepia officinalis

Distribution of oxytocin-like and vasopressin-like immunoreactivities within the central nervous system of the cuttlefish, Sepia officinalis

Neuropeptide Y-immunoreactive neuronal system and colocalization with FMRFamide in the optic lobe and peduncle complex of the octopus (Octopus vulgaris)

The distribution of APGWamide and RFamides in the central nervous system and ovary of the giant freshwater prawn, Macrobrachium rosenbergii

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