Evidence for the increase in the incidence of type 1 diabetes in children aged 0-14 years in the Republika Srpska, 2001-2016

Bukara-Radujković, Gordana; Miljković, Vesna; Ljuboja, Olivera; Lakić, Siniša

doi:10.5457/p2005-114.200

Cited by 2 publications

(4 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The results demonstrate a notable average incidence of type 1 diabetes in Republic of Srpska over the past 25 years, at 12.8/100,000 (95% CI: 10.4-15.1). Comparing with previous reports [6][7][8][9], a slight increase is observed compared to the period 2001-2016 (11/100,000), and a signifi cant increase compared to the period 1998-2010 (7.5/100,000). However, this period has notably fewer cases than the period 2017-2022 (19/100,000).…”

Section: Discussioncontrasting

confidence: 41%

“…Studies conducted in Republic of Srpska [6][7][8], in the neighboring countries [9][10][11][12] and globally [13,14] indicate an upward trend in the number of affected individuals in the 0-14 age group, reflecting a broader phenomenon observed in neighboring regions and worldwide. Discrepancies in reported incidence rates, such as those highlighted by the International Diabetes Federation atlas for Bosnia and Herzegovina, underscore the need for detailed analyses and data consolidation to refine global diabetes statistics [15].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Examining 25-Year Trends of Type 1 Diabetes Incidence in Pediatric Population Aged 0-14 of the Republic of Srpska

Bukara-Radujković

2024

Biomedicinska istraž.

View full text Add to dashboard Cite

Introduction. Data on newly diagnosed cases of type 1 diabetes and the incidence of this disease are very significant. Studies like this one, with an analysis of incidence over the past 25 years, help not only locally but also globally. Methods. The primary source of data is hospital records from hospital centers in Republic of Srpska. The secondary, confirmatory source, is the data from the Health Insurance Fund of Republic of Srpska through which all newly diagnosed patients receive insulin and blood glucose testing strips.&nbsp; Results. The average incidence for the entire period was 12.8/100,000 (95% CI: 10.40&ndash;15.22), with a total of 527 cases, of which 265 (50.3%) were boys. Positive linear trend was observed (R=0.747, R2=0.558, p=0.000018). The annual increase was 0.59 (95% CI: 0.37&ndash; 0.82) or 29.06%. There was no difference between sexes, and the highest incidence, number, and growth were in the age group of 10&ndash;14 years. Discussion. Compared to the period 2001&ndash;2016 (11/100,000) and to the period 1998&ndash;2010 (7.5/100,000), there was the increase in incidence. Significant increase in incidence was observed in the period 2017&ndash;2022. There is no difference from the rest of the world regarding incidence by sex, but there is regarding age group, with the highest incidence in the 10&ndash;14 age group.&nbsp; Conclusion. This research provides a good basis for future studies on the impact of environmental, medical, and other factors on the onset of type 1 diabetes, as well as potential local, national, and global diabetes prevention programs.

show abstract

Section: Discussioncontrasting

confidence: 41%

Section: Introductionmentioning

confidence: 99%

Examining 25-Year Trends of Type 1 Diabetes Incidence in Pediatric Population Aged 0-14 of the Republic of Srpska

Bukara-Radujković

2024

Biomedicinska istraž.

View full text Add to dashboard Cite

show abstract

“…According to the results obtained in this study, we see that the incidence of diabetes mellitus type 1 in the period 2017–2022 increased compared to the period from 2001–2016, from 11/100,000 to 19.5/100,000 children aged 0–14 per year. The linear trend was observed in the period 2001–2016 ( r = 0.71, p ≤ 0.002) ( 4 ). Due to the small number of observed years ( n = 6) in the period from 2017 to 2022, we did not obtain statistically significant results that would confirm a linear trend in this period ( r = 0.31, p ≤ 0.54).…”

Section: Discussionmentioning

confidence: 98%

“…Unfortunately, this unfavorable trend also reflects on our country. The previous study of type 1 diabetes mellitus incidence in the Republic of Srpska for the period from 2001 to 2016, showed that the incidence was 11/100,000 children, which put us in the group of countries with a medium risk for the disease ( 4 ). In that study, the largest number of patients with diabetes mellitus type 1 was in the group of children aged 10–14, unlike most countries where the largest number of patients were in the group of children under 5 years of age, which was explained by the “accelerator hypothesis” ( 5 ).…”

Section: Introductionmentioning

confidence: 99%

Evidence of increasing incidence of type 1 diabetes and ketoacidosis among children in the Republic of Srpska in period 2017–2022 with special focus on COVID-19 global pandemic years

Bukara-Radujkovic,

Miljkovic,

Ljuboja

2023

Front. Public Health

View full text Add to dashboard Cite

Background and objectivesPrimary focus of the research was to determine the incidence of type 1 diabetes mellitus in the period from 2017 to 2022, and whether COVID-19 had an impact on the increase in the number of newly diagnosed children with diabetes type 1 under the age of 15 in the Republic of Srpska (Bosnia and Herzegovina). In the period 2001–2016 the incidence of type 1 diabetes mellitus was 11/100,000, with an annual increasing rate of 14.2%.MethodsAvailable data from pediatric endocrinology clinics, in the Republic of Srpska, on the number of newly diagnosed patients with diabetes mellitus in the period from January 1, 2017 until December 31, 2022 were used. A retrospective analysis was performed, and the capture-recapture method was used for the final assessment, and the obtained result corresponds to about 99% of the population.ResultsThe total number of children in the group of 0–14 years of age diagnosed with type 1 diabetes mellitus in this period was 183, of which 96 (52.46%) were boys, and 87 (47.54%) were girls. The average age at which diabetes mellitus was diagnosed was 8.3 ± 3.9 years. Average incidence of diabetes in the period 2017–2022 was 19/100,000 (95% CI 13.1–25.0). The highest incidence was 28.7/100,000 in 2020, the first year of the global COVID-19 pandemic. Out of a total of 183 newly diagnosed cases in the period 2017–2022, 73 (39.9%) were diagnosed with ketoacidosis upon admission. The largest number of newly diagnosed children was recorded in the group of children aged 10–14 years.ConclusionIn the last 6 years, there has been a significant increase in the incidence of type 1 diabetes mellitus in children under the age of 15. With an incidence of 19.4/100,000 in the Republic of Srpska, we entered the group of countries with high-risk for diabetes. Further steps must focus on the education of the entire society in order to recognize the symptoms of the disease in time and prevent the occurrence of ketoacidosis, which could significantly reduce the burden on health systems, especially in times of global pandemics, such as the COVID-19 pandemic.

show abstract

Evidence for the increase in the incidence of type 1 diabetes in children aged 0-14 years in the Republika Srpska, 2001-2016

Cited by 2 publications

References 12 publications

Examining 25-Year Trends of Type 1 Diabetes Incidence in Pediatric Population Aged 0-14 of the Republic of Srpska

Examining 25-Year Trends of Type 1 Diabetes Incidence in Pediatric Population Aged 0-14 of the Republic of Srpska

Evidence of increasing incidence of type 1 diabetes and ketoacidosis among children in the Republic of Srpska in period 2017–2022 with special focus on COVID-19 global pandemic years

Contact Info

Product

Resources

About