Evidence for the metabolism of capsidiol by a cytochrome P-450-dependent enzyme

Saimmaime, I.; Coulomb, P. J.

doi:10.1016/0031-9422(93)85275-v

Cited by 3 publications

(1 citation statement)

References 19 publications

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“…Ancho San Luis) from local market as previously described (Saimmaime & Coulomb 1993) after injection of cellulase dissolved in sterile H 2 O (8 mg/fruit) as elicitor. After CHCI 3 extraction the solvent was removed in vacuo.…”

Section: Capsidiol Extractionmentioning

confidence: 99%

The effect of acetylation of capsidiol phytoalexin on fungitoxic activity

Arreola-Cortés¹,

Soriano-Bello²,

Lozoya‐Gloria

et al. 2007

Archives Of Phytopathology And Plant Protection

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Natural products have become increasingly sought after as ecologically safer alternatives to herbicides and pesticides, as well as a source of new medicines. However, the biological activity of these compounds is often affected by their stereochemistry, lipophilicity and other factors. Slight modifications can alter the bioactivity either positively or negatively. Capsidiol is the principal phytoalexin of Capsicum annuum. As part of a structure -activity investigation of this phytoalexin, acetylcapsidiol was synthesized and tested in vitro for antifungal activity. Acetyl capsidiol was found to have a low inhibition effect on Aspergillus niger mycelial growth and spore germination. The results suggest that OH groups are indispensable for activity.

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Section: Capsidiol Extractionmentioning

confidence: 99%