Evidence mapping based on systematic reviews of therapeutic interventions for gastrointestinal stromal tumors (GIST)

Ballesteros, Mónica; Montero, Nadia; López‐Pousa, Antonio; Urrútia, Gerard; Solà, Iván; Rada, Gabriel; Pardo-Hernandez, Héctor; Bonfill, Xavier

doi:10.1186/s12874-017-0402-9

Cited by 20 publications

(26 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We followed the approach of the Global Evidence Mapping Initiative [12] with additional components introduced by Ballesteros et al [13][14][15]. We established these criteria a priori in a protocol (available on request).…”

Section: Methodsmentioning

confidence: 99%

Therapeutic use of cannabis and cannabinoids: an evidence mapping and appraisal of systematic reviews

Montero‐Oleas

Arévalo-Rodríguez

Núñez-González

et al. 2020

BMC Complement Med Ther

View full text Add to dashboard Cite

Background: Although cannabis and cannabinoids are widely used with therapeutic purposes, their claimed efficacy is highly controversial. For this reason, medical cannabis use is a broad field of research that is rapidly expanding. Our objectives are to identify, characterize, appraise, and organize the current available evidence surrounding therapeutic use of cannabis and cannabinoids, using evidence maps. Methods: We searched PubMed, EMBASE, The Cochrane Library and CINAHL, to identify systematic reviews (SRs) published from their inception up to December 2017. Two authors assessed eligibility and extracted data independently. We assessed methodological quality of the included SRs using the AMSTAR tool. To illustrate the extent of use of medical cannabis, we organized the results according to identified PICO questions using bubble plots corresponding to different clinical scenarios. Results: A total of 44 SRs published between 2001 and 2017 were included in this evidence mapping with data from 158 individual studies. We extracted 96 PICO questions in the following medical conditions: multiple sclerosis, movement disorders (e.g. Tourette Syndrome, Parkinson Disease), psychiatry conditions, Alzheimer disease, epilepsy, acute and chronic pain, cancer, neuropathic pain, symptoms related to cancer (e.g. emesis and anorexia related with chemotherapy), rheumatic disorders, HIV-related symptoms, glaucoma, and COPD. The evidence about these conditions is heterogeneous regarding the conclusions and the quality of the individual primary studies. The quality of the SRs was moderate to high according to AMSTAR scores. Conclusions: Evidence on medical uses of cannabis is broad. However, due to methodological limitations, conclusions were weak in most of the assessed comparisons. Evidence mapping methodology is useful to perform an overview of available research, since it is possible to systematically describe the extent and distribution of evidence, and to organize scattered data.

show abstract

Section: Methodsmentioning

confidence: 99%

Therapeutic use of cannabis and cannabinoids: an evidence mapping and appraisal of systematic reviews

Montero‐Oleas

Arévalo-Rodríguez

Núñez-González

et al. 2020

BMC Complement Med Ther

View full text Add to dashboard Cite

show abstract

“…This evidence mapping adhered to the PRISMA-Extension for Scoping Reviews 11. It was carried out in accordance with the methodology proposed by GEM,9 adding some previously suggested tasks 12. All methods were specified a priori in a protocol (available on request).…”

Section: Methodsmentioning

confidence: 99%

Evidence mapping and quality assessment of systematic reviews on therapeutic interventions for oral cancer

Anaya¹,

Franco²,

Ballesteros³

et al. 2018

CMAR

Self Cite

View full text Add to dashboard Cite

Purpose: This evidence mapping aims to describe and assess the quality of available evidence in systematic reviews (SRs) on treatments for oral cancer. Materials and methods: We followed the methodology of Global Evidence Mapping. Searches in MEDLINE, EMBASE, Epistemonikos and The Cochrane Library were conducted to identify SRs on treatments for oral cancer. The methodological quality of SRs was assessed using the Assessing the Methodological Quality of Systematic Reviews-2 tool. We organized the results according to identified Population-Intervention-Comparison-Outcome (PICO) questions and presented the evidence mapping in tables and a bubble plot. Results: Fifteen SRs met the eligibility criteria, including 118 individual reports, of which 55.1% were randomized controlled clinical trials. Ten SRs scored "Critically low" methodological quality. We extracted 30 PICOs focusing on interventions such as surgery, radiotherapy, chemotherapy, targeted therapy and immunotherapy; 18 PICOs were for resectable oral cancer, of which 8 were reported as beneficial. There were 12 PICOs for unresectable oral cancer, of which only 2 interventions were reported as beneficial. Conclusion: There is limited available evidence on treatments for oral cancer. The methodological quality of most included SRs scored "Critically low". The main beneficial treatment reported by authors for patients with resectable oral cancer is surgery alone or in combination with radiotherapy or chemotherapy. Evidence about the benefits of the treatments for unresectable oral cancer is lacking. These findings highlight the need to address future research focused on new treatments and knowledge gaps in this field, and increased efforts are required to improve the methodology quality and reporting process of SRs on treatments for oral cancer.

show abstract

“…As a part of an evidence mapping project about sarcomas, we identified, described and organised the current available evidence about soft tissue sarcomas. In a previous paper, we reported the evidence mapping on gastrointestinal stromal tumours (GIST) [13], and now we focus on soft tissue sarcomas. We found 24 SRs including 279 individual studies.…”

Section: Discussionmentioning

confidence: 99%

“…We carried out an evidence map according to the methodology of Global Evidence Mapping (GEM) [10] and adding some new components: an exhaustive search strategy and the assessment of methodological quality of the included systematic reviews (SRs). We divided the process into four stages, the two first stages have been described widely elsewhere [13].…”

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Evidence mapping based on systematic reviews of therapeutic interventions for soft tissue sarcomas

Ballesteros¹,

Montero

López‐Pousa

et al. 2019

Clin Transl Oncol

View full text Add to dashboard Cite

Purpose Soft tissue sarcomas are a heterogeneous group of rare tumours of mesenchymal origin. Evidence mapping is one of the most didactic and friendly approaches to organise and summarise the range of research activity in broad topic fields. The objective of this evidence mapping is to identify, describe and organise the current available evidence about therapeutic interventions on soft tissues sarcomas. Methods We followed the methodology of global evidence mapping. We performed a search of the PubMed, EMBASE, The Cochrane Library and Epistemonikos to identify systematic reviews (SRs) with or without meta-analyses published between 1990 and March 2016. Two independent literature reviewers assessed eligibility and extracted data. Methodological quality of the included systematic reviews was assessed using AMSTAR. We organised the results according to identified PICO questions and used tables and a bubble plot to display the results. Results The map is based on 24 SRs that met eligibility criteria and included 66 individual studies. Three-quarters were either observational or uncontrolled clinical trials. The quality of the included SRs was in general moderate or high. We identified 64 PICO questions from them. The corresponding results mostly favoured the intervention arm. Conclusions This evidence mapping was built on the basis of SRs, which mostly included non-experimental studies and were qualified by the AMSTAR tool as of moderate quality. The evidence mapping created from PICO questions is a useful approach to describe complex and huge clinical topics through graphical media and orientate further research to fulfil the existing gaps. However, it is important to delimitate the steps of the evidence mapping in a pre-established protocol.

show abstract

Evidence mapping based on systematic reviews of therapeutic interventions for gastrointestinal stromal tumors (GIST)

Cited by 20 publications

References 38 publications

Therapeutic use of cannabis and cannabinoids: an evidence mapping and appraisal of systematic reviews

Therapeutic use of cannabis and cannabinoids: an evidence mapping and appraisal of systematic reviews

Evidence mapping and quality assessment of systematic reviews on therapeutic interventions for oral cancer

Evidence mapping based on systematic reviews of therapeutic interventions for soft tissue sarcomas

Contact Info

Product

Resources

About