Evidence of non‐linearity in the association of glycemic control with influenza/pneumonia mortality: a study of 19 000 adults from the US general population

Abstract

Future studies on diabetes and infections should adequately address potential non-linearity, which may be necessary to better understand and characterize more precisely the relationship of diabetes with infectious diseases.

Pneumonia in the Noninstitutionalized Older Population

“…Some of the associations pointed out here merit more detailed characterization in the future. For example, an analysis including consideration of the duration of diabetes and the results of treatment might shed light on the question of a possibly higher incidence of pneumonia in some subgroups of patients with diabetes mellitus (29).…”

Development of a prediction tool for patients presenting with acute cough in primary care: a prognostic study spanning six European countries

“…Although the authors included a lot of variables in building this prediction model, note that they were not able to include some covariates that have previously been shown to increase the risk of hospitalisation or death from pneumonia, for example, high blood glucose levels and the use of proton pump inhibitors. 22,23 Comparison with existing literature Currently, there are no prediction rules for poor outcome in adults presenting to primary care with acute cough. The only alternative available is the use of prognostic prediction rules that were developed to predict mortality in patients presenting to the emergency department with CAP (for example, PSI and CRB).…”

Emerging infections—an increasingly important topic: review by the Emerging Infections Task Force

“…With ageing comes increased prevalence of risk factors for infection and the outcomes thereof. The prevalence of diabetes is rapidly increasing globally, leading to increased risk of complications to infections including tuberculosis [39], SARS [40], influenza [41], pneumococcal infections [42] and MERS-CoV. Age-related diseases like cancers are followed by immunosuppressive therapy and will result in individuals susceptible to infections including emerging and reemerging infections.…”