Evidence that 3-keto petromyzonol sulphate specifically attracts ovulating female sea lamprey, Petromyzon marinus

Siefkes, Michael J.; Winterstein, Scott R.; Li, Weiming

doi:10.1016/j.anbehav.2005.01.024

Cited by 85 publications

(80 citation statements)

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“…Female behaviors were assumed to be independent as observed from earlier studies (7,16). Binary data from experiments with more than two treatment groups were evaluated with logistic regression and models showed no evidence of overdispersion or nonlinearities.…”

Section: Methodsmentioning

confidence: 99%

“…Given that most characterized pheromones are mixtures that only elicit strong responses when all components are present (17), it was interesting to observe that 3kPZS alone induced robust upstream movements over long distances and ranges of concentrations. It has been hypothesized that spermiated male washings (SMW) contain additional pheromone components (18) that induce near source search behaviors in ovulated females (7). Thus, we wished to confirm the role of 3kPZS-mediated upstream movement when placed in the context of SMW by directly comparing responses of ovulated females to synthesized 3kPZS and SMW over long and short distances.…”

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confidence: 99%

“…Previously, we found behavioral responses of ovulated females to spermiated males or their washings in a twochoice maze do not differ (7). In a natural stream, traps baited with spermiated males and SMW both capture large proportions of ovulated females (16,19).…”

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confidence: 99%

“…Studies of pheromone-mediated behavior of vertebrates in natural habitats have been limited both because relatively few vertebrate pheromones have been chemically identified (3) and because field research on this topic is often constrained by the ecology and behavior of vertebrates (4). Nonetheless, studies of the sea lamprey (Petromyzon marinus), an ancestral vertebrate and destructive invader of the Laurentian Great Lakes (5), indicate that spermiated males release a pheromone, 7␣, 12␣, 24-trihydroxy-5␣-cholan-3-one 24-sulfate (3kPZS) (6), that induces predictable movements in ovulated females in spawning streams (7). We reasoned that the sea lamprey offers a uniquely advantageous model for determining possible applications of pheromones in vertebrate pest control.…”

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confidence: 99%

“…Over 3,000 insect pheromones have been identified (13) and mixtures of female pheromones are commonly used as agents to enhance male trapping efficiency and disrupt reproduction as benign alternatives to traditional pesticide treatments (14). 3kPZS offers an ideal model for developing pheromone-based vertebrate pest control because, unlike mixtures of insect pheromones that attract males, 3kPZS alone modifies the behavior of ovulated females in their natural habitat (7). Further, 3kPZS is the first synthesized vertebrate pheromone in which an experimental user permit from US Environmental Protection Agency has been issued to allow application in a natural stream.…”

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confidence: 99%

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A synthesized pheromone induces upstream movement in female sea lamprey and summons them into traps

Johnson

Yun

Thompson

et al. 2009

Proc. Natl. Acad. Sci. U.S.A.

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166

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Female insect pheromone blends induce robust tracking responses in males and direct them into traps. In vertebrates, pheromones that induce strong and precise tracking responses in natural habitats have rarely been described. Here, we show in the sea lamprey (Petromyzon marinus), a vertebrate invader of the Laurential Great Lakes, that a synthesized component of the male mating pheromone, 7␣, 12␣, 24-trihydroxy-5␣-cholan-3-one 24-sulfate (3kPZS), when released into a stream to reach concentrations of 10 ؊14 , 10 ؊13 , 10 ؊12 ,10 ؊11 , or 10 ؊10 M, triggers robust upstream movement in ovulated females drawing Ϸ50% into baited traps. Experiments conducted in diverse stream segments demonstrate the level of behavioral response was not affected by habitat conditions and is effective over hundreds of meters. 3kPZS is equally effective at luring ovulated females as the whole pheromone blend released by males between 10 ؊14 and 10 ؊11 M. 3kPZS diverts ovulated females away from and disrupts orientation to male washings when applied at concentrations higher than washings. Indeed, a single pheromone compound is able to redirect female sea lampreys away from a natural pheromone source and lure them into traps, which should be more effective than targeting males when applied in population control. Our findings may spur the discovery of other potent and environmentally benign agents to combat biological invasion, a process accelerated by globalization, exacerbated by climate change, and costing the global economy US$ 1.4 trillion of damage annually.invasive species ͉ odorant tracking ͉ pest control ͉ odorant disruption ͉ jawless vertebrate

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Section: Methodsmentioning

confidence: 99%

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confidence: 99%

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confidence: 99%

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confidence: 99%

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