Evidence that Food Proteins in Vaccines Cause the Development of Food Allergies and Its Implications for Vaccine Policy

doi:10.4172/2329-6631.1000137

Cited by 3 publications

(1 citation statement)

References 15 publications

(23 reference statements)

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“…However, now, for the vast majority of the world's population, helminth and parasite infections are rare. The main cause of IgE mediated sensitization is vaccines (Arumugham 2015). Most injected proteins can be expected to cause IgE mediated sensitization and an allergic reaction/anaphylaxis upon subsequent exposure.…”

Section: Prediction Of Covid-19 Immunopathologymentioning

confidence: 99%

Immunological Mechanisms Explaining the Role of Vaccines, IgE, Mast Cells, Histamine, Elevating Ferritin, IL-6, D-dimer, VEGF Levels in COVID-19 and Dengue, Potential Treatments Such as Mast Cell Stabilizers, Antihistamines: Predictions and Confirmations

Arumugham¹

2020

SSRN Journal

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A novel coronavirus, SARS-CoV-2 was identified in Wuhan, China. The disease caused by the virus can range in severity from asymptomatic to acute respiratory distress syndrome (ARDS) and death. Primary dengue infection results in IgE mediated sensitization against dengue virus proteins. These IgE bind to receptors on mast cells. Upon subsequent exposure to the antigen recognized by the IgE, mast cell degranulation occurs releasing mediators such as histamine. Therefore secondary dengue infection results in urticaria, increased vascular permeability, hypotension, dengue hemorrhagic fever and dengue shock syndrome. A case of "slow rolling anaphylaxis". Vaccines contain proteins derived from coronavirus infected animals as well as other proteins with high homology to SARS-CoV-2. So one could develop IgE mediated sensitization to SARS-CoV-2-like proteins. Therefore, receipt of such vaccines acts like a dengue "primary infection". It results in IgE mediated sensitization. Subsequent SARS-CoV-2 infection becomes a "secondary dengue infection" that has a severe course due to IgE mediated mast cell degranulation and the immune cascade that follows. There are many common observations between COVID-19 and dengue. Elevated levels of ferritin, interleukin-6, vascular endothelial growth factor, D-dimer, coagulopathy, urticaria and ARDS are reported in both diseases. Numerous teams have now confirmed this mechanism that was predicted in Jan 2020, upon analyzing the 2019-nCoV proteome. There are many indicators that mast cell degranulation and histamine release have a major role in COVID-19, dengue and influenza severity. Mast cell stabilizers, antihistamines and anti-parasite treatments may address different aspects of this cascade and thus reduce disease severity.

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Section: Prediction Of Covid-19 Immunopathologymentioning

confidence: 99%

Immunological Mechanisms Explaining the Role of Vaccines, IgE, Mast Cells, Histamine, Elevating Ferritin, IL-6, D-dimer, VEGF Levels in COVID-19 and Dengue, Potential Treatments Such as Mast Cell Stabilizers, Antihistamines: Predictions and Confirmations

Arumugham¹

2020

SSRN Journal

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IgE reactivity to milk components in dogs with cutaneous adverse food reactions

Shimakura

Nasukawa

Uchiyama

et al. 2021

The Journal of Veterinary Medical Science

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We investigated the IgE reactivity to crude and purified milk antigens in the sera of 112 dogs with cutaneous adverse food reactions (CAFRs). Of the 112 dogs, 33 (29%) had specific IgE for crude milk antigens. In the dogs with milk-specific IgE, IgE reactivity to casein, bovine serum albumin (BSA), α-lactalbumin, β-lactoglobulin, and bovine IgG were 81%, 85%, 39%, 27%, and 35%, respectively. Casein and BSA may be important allergens in dogs with CAFRs. Some canine vaccines contain casein hydrolysate as a stabilizer and the pooled serum with anti-casein IgE showed IgE reactivity to the vaccines containing it. Information about IgE reactivity to casein in dogs with CAFRs could be useful for predicting adverse reactions to the vaccines including casein hydrolysate.

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Credit Where Credit Is Due: Cow'S Milk Contaminated Vaccines Prevent Cancer ... By Causing Autism

Arumugham¹

2017

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Evidence that Food Proteins in Vaccines Cause the Development of Food Allergies and Its Implications for Vaccine Policy

Cited by 3 publications

References 15 publications

Immunological Mechanisms Explaining the Role of Vaccines, IgE, Mast Cells, Histamine, Elevating Ferritin, IL-6, D-dimer, VEGF Levels in COVID-19 and Dengue, Potential Treatments Such as Mast Cell Stabilizers, Antihistamines: Predictions and Confirmations

Immunological Mechanisms Explaining the Role of Vaccines, IgE, Mast Cells, Histamine, Elevating Ferritin, IL-6, D-dimer, VEGF Levels in COVID-19 and Dengue, Potential Treatments Such as Mast Cell Stabilizers, Antihistamines: Predictions and Confirmations

IgE reactivity to milk components in dogs with cutaneous adverse food reactions

Credit Where Credit Is Due: Cow'S Milk Contaminated Vaccines Prevent Cancer ... By Causing Autism

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