Evidence that haloperidol impairs learning and motivation scores in a probabilistic task by reducing the reward expectation

Negrelli, Bernadete; Pochapski, José Augusto; Villas-Boas, Cyrus Antonio; Jessen, Leticia F.; Teixeira, Mayra Aline Lopes; Cunha, Cláudio Da

doi:10.1016/j.bbr.2020.112858

Cited by 2 publications

(2 citation statements)

References 32 publications

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“…Specifically, the lack of the habituation phenomenon in rats exposed to HALO before the first test but treated with SAL before the retest appears to be due to differences in the subject's internal state between the first test and retest. Pharmacological treatment, including the administration of HALO, has profound effects on the subject's internal state, e.g., as reflected by its effect on reward expectation (Negrelli et al, 2020) and the emission of 50-kHz USV (Wright et al, 2013), and it was repeatedly shown that a mismatch of the subject's internal state during acquisition, i.e., the first test, and retrieval, i.e., the retest, hinders memory retrieval (e.g., Girden and Culler, 1937; for review see Radulovic et al, 2017). For instance, in a T-maze escape task, rats were not able to display a response learned under drugged conditions in later undrugged conditions (Overton, 1964).…”

Section: Access Isciencementioning

confidence: 99%

Limited generalizability, pharmacological modulation, and state-dependency of habituation towards pro-social 50-kHz calls in rats

et al. 2021

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Communication constitutes a fundamental component of mammalian social behavior. Rats are highly social animals and emit 50-kHz ultrasonic vocalizations (USV), which function as social contact calls. Playback of 50-kHz USV leads to strong and immediate social approach responses in receiver rats, but this response is weak or even absent during repeated 50-kHz USV playback. Given the important role of 50-kHz USV in initiating social contact and coordinating social interactions, the occurrence of habituation is highly unexpected. It is not clear why a social signal characterized by significant incentive salience loses its power to change the behavior of the receiver so rapidly. Here, we show that the habituation phenomenon displayed by rats in response to repeated playback of 50-kHz USV (1) is characterized by limited generalizability because it is present in Wistar but not Sprague-Dawley rats, (2) can be overcome by amphetamine treatment, and (3) depends on the subject's internal state.

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Section: Access Isciencementioning

confidence: 99%

Limited generalizability, pharmacological modulation, and state-dependency of habituation towards pro-social 50-kHz calls in rats

et al. 2021

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“…Pengaturan sistem penghargaan dirancang dengan tujuan untuk meningkatkan produktivitas, loyalitas, dan kedisiplinan siswa (Purnawinadi, 2018). Karena itu, penting untuk melakukan analisis yang teliti terhadap cara pemberian reward dapat memengaruhi motivasi belajar siswa secara menyeluruh (Gewerc, 2023;Negrelli, 2020;Piazzalunga, 2023).…”

Section: Pendahuluanunclassified

Analisis Dampak Pemberian Reward terhadap Motivasi Belajar Siswa Kelas VA SDN 106162 Kecamatan Percut Sei Tuan

Nainggolan,

Lesmana,

Syahrial

2024

pgsd

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Tujuan dari penelitian ini adalah untuk mengetahui dampak pemberian reward bagi siswa Siswa Kelas VA SDN 106162 Peneliti menggunakan pendekatan deskriptif kualitatif dengan metode observasi, wawancara. Lokasi penelitian dilaksanakan di SDN 106162, Desa Medan Estate, Kecamatan Percut Sei Tuan. Teknik analisis data dalam penelitian ini menggunakan reduksi data, penyajian data, dan penarikan kesimpulan. Hasil analisis dampak pemberian reward terhadap motivasi belajar siswa dikelas VA, menunjukkan bahwa penggunaan reward memiliki efek positif terhadap motivasi belajar siswa, partisipasi, dan antusiasme. Reward dalam berbagai bentuk, baik non-materi (pujian, tepuk tangan) maupun materi (permen, pensil warna), dapat meningkatkan keaktifan siswa dalam bertanya, menjawab, dan mengerjakan soal.

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Evidence that haloperidol impairs learning and motivation scores in a probabilistic task by reducing the reward expectation

Cited by 2 publications

References 32 publications

Limited generalizability, pharmacological modulation, and state-dependency of habituation towards pro-social 50-kHz calls in rats

Limited generalizability, pharmacological modulation, and state-dependency of habituation towards pro-social 50-kHz calls in rats

Analisis Dampak Pemberian Reward terhadap Motivasi Belajar Siswa Kelas VA SDN 106162 Kecamatan Percut Sei Tuan

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