Evolution and Scientific Impact of Research Grants From the Spanish Society of Cardiology and Spanish Heart Foundation (2000-2006)

Benavent, Rafael Aleixandre; Arroyo, Adolfo Alonso; Sánchez, Manuel Anguita; Bolaños-Pizarro, Máxima; Heras, Magda; Alcalde, Gregorio González; Miguel, Carlos Macaya; Navarro-Molina, Carolina; Castelló‐Cogollos, Lourdes; Valderrama‐Zurián, Juan Carlos; Gascó, Francisco de Paula Blasco; Martínez, Vicente Bertoméu; Taboada, M.; Celemín, Leandro Plaza; Pérez-Villacastín, Julián; Fillat, Ángel Cequier; Román, Alfonso Varela; Zaldumbide, E. Laraudogoitia; Cabedo, S. Morell

doi:10.1016/j.rec.2011.03.022

Cited by 6 publications

(5 citation statements)

References 36 publications

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“…The majority of the population are covered by the Spanish National Health System. Moreover, this region is a reference region in health research in Spain [14,15], particularly for the study of fibromyalgia and of the effects of exercise internationally [16]. A total of 17 of these FM patients had a previous CFS diagnosis (FM + CFS group) and the remaining 17 were FM patients without a CFS codiagnosis (FM group).…”

Section: Participants and Experimental Designmentioning

confidence: 99%

“…The Spanish version of Beck's Depression Inventory developed by Sanz and coworkers [17] was used to determine the presence of signs of depression. Higher scores are associated with greater signs of depression and according to the final score, perceived depression can be classified as: mild (10)(11)(12)(13)(14)(15)(16)(17)(18)(19), moderate (20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30), or severe (>30) [18].…”

Section: Subjective Quality Of Lifementioning

confidence: 99%

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Influence of Chronic Fatigue Syndrome Codiagnosis on the Relationship between Perceived and Objective Psychoneuro-Immunoendocrine Disorders in Women with Fibromyalgia

et al. 2023

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Although the predominant symptom in fibromyalgia (FM) is muscle pain, and fatigue in chronic fatigue syndrome (CFS), differential diagnosis is very difficult. This research investigates the psychoneuroimmunoendocrine disorders of FM patients and ascertains whether a previous CFS diagnosis affected them. Through accelerometry objective parameters, physical activity/sedentarism levels in relation to fatigue are studied, as well as whether perceived levels of stress, anxiety, and pain correspond to objective biomarkers, all of these with respect to a reference group (RG) of women without FM. FM patients have a worse psychological state and perceived quality of life than those with RG. These perceived outcomes are consistent with impaired objective levels of a sedentary lifestyle, higher systemic levels of cortisol and noradrenaline, and lower levels of serotonin. However, FM patients with a previous CFS diagnosis had lower systemic levels of IL-8, cortisol, oxytocin, and higher levels of adrenaline and serotonin than FM patients without diagnosed CFS. In conclusion, while perceived health parameters do not detect differences, when objective neuroimmunoendocrine parameters related to stress, inflammation, pain, and fatigue are used, people with CFS could be overdiagnosed with FM. This reinforces the need for objective biomarker assessment of these patients for better diagnostic discrimination between both syndromes.

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Section: Participants and Experimental Designmentioning

confidence: 99%

Section: Subjective Quality Of Lifementioning

confidence: 99%

Influence of Chronic Fatigue Syndrome Codiagnosis on the Relationship between Perceived and Objective Psychoneuro-Immunoendocrine Disorders in Women with Fibromyalgia

et al. 2023

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“…These studies have been carried out in patients belonging to different associations from the autonomous community of Extremadura (Spain). The population, due to its socio-sanitary characteristics, lifestyle, and follow-up by the public health system, has already been referred to in many studies as suitable for scientific studies on health and well-being [ 15 , 16 ]. Additionally, in terms of FM, this region is a reference throughout Europe due to the abundance of research, from different approaches, by different groups.…”

Section: Discussionmentioning

confidence: 99%

“…The majority of the population is assisted by the Spanish National Health System, in which patient associations play a relevant role. Extremadura is also a reference region in Spain in health research [ 15 , 16 ], and particularly in patients with fibromyalgia and in the effects of exercise internationally.…”

Section: Methodsmentioning

confidence: 99%

Influence of Codiagnosis of Chronic Fatigue Syndrome and Habitual Physical Exercise on the Psychological Status and Quality of Life of Patients with Fibromyalgia

Hinchado

Otero

Navarro

et al. 2022

JCM

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Fibromyalgia (FM) and Chronic Fatigue Syndrome (CFS) are two diseases that are frequently codiagnosed and present many similarities, such as poor tolerance to physical exercise. Although exercise is recommended in their daily routine to improve quality of life, little is known about how CFS codiagnosis affects that. Using scientifically validated questionnaires, we evaluated the psychological state and quality of life of patients with FM (n = 70) and how habitual physical exercise (HPE) reported by patients with only FM (FM-only n = 38) or codiagnosed with CFS (FM + CFS, n = 32) influences those aspects. An age-matched reference group of “healthy” women without FM (RG, n = 70) was used. The FM-only group presented a worse psychological state and quality of life compared to RG, with no influence of CFS codiagnosis. The patients of the FM-only and FM + CFS groups who perform HPE presented better levels of stress and state anxiety, but with no differences between them. Depression and trait anxiety improved only in women with just FM. CFS codiagnosis does not worsen the psychological and quality of life impairment of FM patients and does not have a great influence on the positive effect of HPE.

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“…This study was carried out on 68 women diagnosed with FM (FM patient group) belonging to the FM association EXISTIMOS ® (Badajoz, Extremadura, Spain; Extremadura is a reference region in the FM investigation due to the homogeneous population in terms of lifestyle [28,29]). All participants included in the study were within the age range of 40 to 65 years.…”

Section: Participants and Experimental Designmentioning

confidence: 99%

Subjective Sleep Quality Versus Objective Accelerometric Measures of Sleep and Systemic Concentrations of Sleep-Related Hormones as Objective Biomarkers in Fibromyalgia Patients

et al. 2023

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Poor quality of sleep leads to an increase in severity of the symptoms associated with fibromyalgia (FM) syndrome and vice versa. The aim of this study was to determine if the poor perceived sleep quality in FM patients could be corroborated by objective physiological determinations. Perceived sleep quality was evaluated (through the Pittsburgh Sleep Quality Index) in 68 FM patients compared to an age-matched reference group of 68 women without FM. Objective sleep quality (measured using accelerometry), and systemic concentrations of sleep-related hormones (catecholamines, oxytocin, serotonin, and melatonin) were evaluated in two representative groups from the reference control group (n = 11) and FM patients (n = 11). FM patients reported poorer subjective sleep quality compared to the reference group. However, no significant differences were found in accelerometry parameters, except for a delay in getting in and out of bed. In addition, FM patients showed no significant differences in oxytocin concentration and adrenaline/noradrenaline ratio, as well as a lower serotonin/melatonin ratio. Poor perception of sleep quality in FM patients does not correspond to objective determinations. A dysregulation of the stress response could be associated with the delay in their resting circadian rhythm and difficulty falling asleep. This would be the cause that justifies the perceived lack of rest and the fatigue they feel when waking up.

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Evolution and Scientific Impact of Research Grants From the Spanish Society of Cardiology and Spanish Heart Foundation (2000-2006)

Cited by 6 publications

References 36 publications

Influence of Chronic Fatigue Syndrome Codiagnosis on the Relationship between Perceived and Objective Psychoneuro-Immunoendocrine Disorders in Women with Fibromyalgia

Influence of Chronic Fatigue Syndrome Codiagnosis on the Relationship between Perceived and Objective Psychoneuro-Immunoendocrine Disorders in Women with Fibromyalgia

Influence of Codiagnosis of Chronic Fatigue Syndrome and Habitual Physical Exercise on the Psychological Status and Quality of Life of Patients with Fibromyalgia

Subjective Sleep Quality Versus Objective Accelerometric Measures of Sleep and Systemic Concentrations of Sleep-Related Hormones as Objective Biomarkers in Fibromyalgia Patients

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