Hyaluronic acid (HA) fillers are commonly used for aesthetic purposes. HA filler injections are the second most frequently used nonsurgical aesthetic procedure in the world, following botulinum toxin injections. 1 Limited allergic reactivity, the availability of an antidote, rapid recovery, and a wide selection of products fulfilling different aesthetic goals make HA fillers popular. Despite their popularity, the tear trough has been considered the most challenging area to treat with HA. [2][3][4] HA is a naturally occurring glycosaminoglycan in living organisms that is one of the basic components of the dermis and all connective tissue. 5 Although HA fillers have been thought to be relatively safe, adverse effects can occur, ranging from mild to severe in intensity. Dermal filler complications can be categorized according to the time of appearance (early, late, and delayed onset). Early onset complications include temporary bruising, edema, erythema at the injection site, and vascular compromise (retinal artery occlusion, tissue necrosis, ischemic changes) which is a major complication. Late-onset complications include atypical infections and inflammation, migration of implant material, persistent discoloration and scarring, and foreignbody granuloma formation. 6,7 All injectable dermal fillers may cause foreign-body granulomas whose incidence is 0.01% to 1%. 7,8 To our knowledge, there has been no study reporting very lateterm orbital mass formation secondary to HA filler injection into the inferior eyelid. We report two cases of right infraorbital palpable mass 10 years after filler injection in patients who underwent orbitotomy due to the concern of a potential orbital tumor according to the clinical examination and magnetic resonance imaging (MRI)