Evolution of clinical and translational advances in the management of pediatric arteriovenous malformations

See, Alfred P.; Smith, Edward

doi:10.1007/s00381-023-06077-x

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Advances In Interventional Radiology1

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2024

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“…The advent of the modern era of interventional radiology has ushered in a sea-change in the ability to visualize and treat AVMs and VOGMs. High-quality three-dimensional angiography can now be performed safely in the pediatric population, employing catheters and devices that are small enough for superselective access to individual pedicles in children [ 30 , 50 ]. The creation of detachable-tip and steerable microcatheters have been seminal to this progress, enabling interventional radiologists to reach crucial regions of vascular malformations for diagnostic and therapeutic access [ 13 , 27 , 32 ].…”

Section: Advances In Interventional Radiologymentioning

confidence: 99%

Pediatric Cerebral Vascular Malformations : Current and Future Perspectives

Smith

2024

J Korean Neurosurg Soc

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Intracranial vascular malformations typically encountered by pediatric neurosurgeons include arteriovenous malformations, vein of Galen malformations and cavernous malformations. While these remain amongst some of the most challenging lesions faced by patients and caregivers, the past decade has produced marked advances in the understanding of the pathophysiology of these conditions, with concomitant innovations in treatment. This article will highlight present and future perspectives relevant to these diseases, with a focus on an emerging approach utilizing disease-specific mutations to develop a novel taxonomy for these conditions.

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