Evolution of Concepts and Technologies in Ophthalmic Laser Therapy

Palanker, Daniel

doi:10.1146/annurev-vision-111815-114358

Cited by 12 publications

(7 citation statements)

References 97 publications

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“…Laser interaction with human tissue depends on the laser wavelength, pulse duration, and irradiance (energy per area) [5]. Modern retinal photocoagulators are usually Yellow 577 nm or double frequency Nd: Yag 532 lasers.…”

Section: Principles Of Retinal Photocoagulation and Micropulse Lasmentioning

confidence: 99%

Micropulse Laser Treatment of Retinal Diseases

Gawęcki¹

2019

JCM

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Subthreshold micropulse laser treatment has been intensively used for selected retinal diseases in the last decade; however, the exact mechanism of the action of lasers in the subthreshold micropulse mode is not yet fully understood. This kind of treatment is safe and cheap, and contrary to classic laser photocoagulation, it leaves the retinal cells intact. A modern theory of micropulse laser interaction with retinal tissue and a possible explanation of this mechanism are presented in this review. The authors present all the relevant literature on the application of micropulse lasers in different retinal disorders. The efficacy of this treatment is analyzed on the basis of available studies and then placed in the perspective of other therapeutic methods that are used in retinal diseases.

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Section: Principles Of Retinal Photocoagulation and Micropulse Lasmentioning

confidence: 99%

Micropulse Laser Treatment of Retinal Diseases

Gawęcki¹

2019

JCM

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“…[1,24] Due to the aforementioned properties of the laser, it began to be used in various fields as dermatology, otorhinolaryngology, urology, general surgery, and ophthalmology. [10,14,16,20,22] e mechanism by which the laser works is through the conversion of the light energy absorbed by the tissue to heat with subsequent coagulation or vaporization of the target and in extremely high energies its photomechanical destruction. [1] e first CO2 laser was created by Patel [21] and it is the most widely used in neurosurgery today [3,15] as brain tissue contains approximately 80% water [19] and CO2 laser energy gets highly absorbed in water thus providing minimal thermal damage to surrounding tissue.…”

Section: Introductionmentioning

confidence: 99%

The evaluation of the usefulness of CO₂ laser in microsurgical resection of brain tumors

Nerntengian

Tanrikulu

Manoussos

et al. 2022

Surgical Neurology International

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Background: Since its introduction to surgery, the CO2 laser has been used in the treatment of various neurosurgical pathologies as it combines cutting, vaporizing, and coagulating properties in one tool and has a safe penetration depth. In this case series of 29 patients, we present the evaluation of the usefulness of the closed system type – sealed tube surgical CO2 laser in the surgical removal of brain tumors. Methods: The Sharplan 40C model SurgiTouch, sealed tube type CO2 laser, was used in the resection of 29 brain tumors; 13 meningiomas, six metastases, nine gliomas, and one acoustic neuroma. The same senior surgeon (BT) assessed and classified the benefit provided by the CO2 laser in the resection of the neoplasms to considerable (Group 1), moderate (Group 2), and poor (Group 3). Results: Group 1 included 14 patients with 13 meningiomas and one acoustic neuroma, Group 2 included six patients, all of whom had metastases, and Group 3 included nine patients of which six had glioblastoma and three astrocytoma. No complications or technical problems occurred due to the use of the CO2 laser. Conclusion: The CO2 laser is a valuable complementary tool in brain tumor surgery displaying high efficacy and practicality in the resection of neoplasms which are fibrous and have hard consistency. It has high acquisition and maintenance cost and cannot replace the bipolar diathermy. The newest generation of flexible CO2 laser fiber provides more ergonomy and promises new perspectives of its neurosurgical use in the modern era.

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“…The laser power is titrated to create a barely visible lesion at a pulse duration of 15 or 20 milliseconds, and EpM using 15 milliseconds is called NRT [5,6]. The yellow laser (577 nm) is suitable for macular disease.…”

Section: -Introductionmentioning

confidence: 99%

Nondamaging retinal laser therapy in recurrent diabetic macular edema after anti- VEGF injections

Çıtırık¹

2021

Turk J Med Sci

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Background/Aim: Subthreshold yellow non-damaging retinal laser therapy (NRT) could provide a greater safety profile when compared to conventional laser methods. NRT may also improve diabetic macular edema (DME). This study aims to assess whether the severity of DME affects the efficacy of subthreshold yellow NRT. Methods:The study included 70 eyes that had previously been treated with ranibizumab for DME and then developed recurrent macular edema, which was treated with NRT once. The central foveal thickness (CFT) and best-corrected visual acuity (BCVA) were evaluated retrospectively 2 months following the NRT. The eyes in the study were divided into 4 different groups according to the baseline CFT values. The initial CFT was 250-300 μm in Group 1 (n=26), 301-400 μm in Group 2 (n=24), and >401 μm in Group 3 (n=20). Group 4 (n=20) included control subjects with 250-300 µm CFT, diagnosed with DME, and not previously treated. The alterations in the BCVA and CFT were measured.Results: In the study, it was determined that 45 right eyes and 45 left eyes were involved.Statistically significant decrements (42.84 m reduction) in CFT were detected only in the Group 1 (p=0.01). There was no significant improvement in CFT within Group 2, 3 and 4 (p= 0.29, p= 0.73, p= 0.22, respectively). Solely Group 1 had statistically significant improvement (from 0.54 to 0.39 LogMAR) in BCVA (p= 0.01), while groups 2, 3 and 4 had no improvement at all (p=0.74, p=0.96, p=0.66 respectively). Conclusions:Based on the results, NRT provided an improvement in BCVA and CFT in eyes with CFT less than 300 µm at the short-term follow-up. However, CFT and BCVA 2 outcomes after NRT were inferior to those achieved after previous ranibizumab treatment. No positive effect of NRT was not observed in patients with moderate and severe macular edema in DME treatment.

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Evolution of Concepts and Technologies in Ophthalmic Laser Therapy

Cited by 12 publications

References 97 publications

Micropulse Laser Treatment of Retinal Diseases

Micropulse Laser Treatment of Retinal Diseases

The evaluation of the usefulness of CO₂ laser in microsurgical resection of brain tumors

Nondamaging retinal laser therapy in recurrent diabetic macular edema after anti- VEGF injections

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Evolution of Concepts and Technologies in Ophthalmic Laser Therapy

Cited by 12 publications

References 97 publications

Micropulse Laser Treatment of Retinal Diseases

Micropulse Laser Treatment of Retinal Diseases

The evaluation of the usefulness of CO2 laser in microsurgical resection of brain tumors

Nondamaging retinal laser therapy in recurrent diabetic macular edema after anti- VEGF injections

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The evaluation of the usefulness of CO₂ laser in microsurgical resection of brain tumors