Evolution of crossover interference enables stable autopolyploidy by ensuring pairwise partner connections in Arabidopsis arenosa

Morgan, Chris; White, Merry; Franklin, F. Chris H.; Zickler, Denise; Kleckner, Nancy; Bomblies, Kirsten

doi:10.1016/j.cub.2021.08.028

Cited by 57 publications

(104 citation statements)

References 90 publications

(178 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These data support the idea that either the reduction of CO frequency or the increase of CO interference promote the formation of bivalents over multivalents, to achieve balanced chromosome segregation during meiosis in polyploids [ 234 ]. Indeed, CO interference, measured by localizing E3 ligase HEI10 foci, is strong in established autotetraploid plants of A. arenosa , but weak in synthetic neotetraploids of this species [ 235 ]. In this context, it is important to highlight that the reduction in chiasma frequency has also been observed in other established autotetraploid species [ 236 ].…”

Section: Cytological Diploidization Of Allopolyploidsmentioning

confidence: 99%

Genomic and Meiotic Changes Accompanying Polyploidization

Blasio

Prieto

Pradillo

et al. 2022

Plants

View full text Add to dashboard Cite

Hybridization and polyploidy have been considered as significant evolutionary forces in adaptation and speciation, especially among plants. Interspecific gene flow generates novel genetic variants adaptable to different environments, but it is also a gene introgression mechanism in crops to increase their agronomical yield. An estimate of 9% of interspecific hybridization has been reported although the frequency varies among taxa. Homoploid hybrid speciation is rare compared to allopolyploidy. Chromosome doubling after hybridization is the result of cellular defects produced mainly during meiosis. Unreduced gametes, which are formed at an average frequency of 2.52% across species, are the result of altered spindle organization or orientation, disturbed kinetochore functioning, abnormal cytokinesis, or loss of any meiotic division. Meiotic changes and their genetic basis, leading to the cytological diploidization of allopolyploids, are just beginning to be understood especially in wheat. However, the nature and mode of action of homoeologous recombination suppressor genes are poorly understood in other allopolyploids. The merger of two independent genomes causes a deep modification of their architecture, gene expression, and molecular interactions leading to the phenotype. We provide an overview of genomic changes and transcriptomic modifications that particularly occur at the early stages of allopolyploid formation.

show abstract

Section: Cytological Diploidization Of Allopolyploidsmentioning

confidence: 99%

Genomic and Meiotic Changes Accompanying Polyploidization

Blasio

Prieto

Pradillo

et al. 2022

Plants

View full text Add to dashboard Cite

show abstract

“…Polyploids possess multiple advantages that make ploidy an intriguing tool for crop improvement and a key phenomenon in adaptive evolution in nature. However, newly formed (neo)polyploids often also exhibit meiotic irregularities that compromise their genome stability and fertility [ 4 , 5 , 6 , 7 , 8 , 9 ].…”

Section: Suppression Of Meiotic Defects In Polyploids In Plantsmentioning

confidence: 99%

“…A subset of recombinational interactions eventually mature into meiotic crossovers [ 11 ] that, along with sister chromatid cohesion, physically link homologous chromosomes (cytologically visualized as chiasmata during metaphase I) in pairs called bivalents that later segregate towards opposite poles in anaphase I [ 12 ]. In neopolyploids, multiple homologous partners are suddenly present, and promiscuous interactions can arise among them, leading to so-called multivalents ( Figure 1 a) that can lead to chromosome mis-segregation [ 4 , 5 , 9 , 13 ].…”

Section: Suppression Of Meiotic Defects In Polyploids In Plantsmentioning

confidence: 99%

“…The pervasiveness of stable and fertile polyploids in both crops and wild plants demonstrates that, after WGD, a specialized meiotic program can evolve that prevents promiscuous interactions and consequent meiotic irregularities [ 9 , 14 , 15 ]. This process of evolving adjustments to suppress meiotic defects is referred to as cytological diploidization ( Figure 1 a), because it results in a diploid-like cytologically observable meiosis [ 16 ].…”

Section: Suppression Of Meiotic Defects In Polyploids In Plantsmentioning

confidence: 99%

“…In the last decade, there has been substantial progress in understanding the genic [ 19 , 20 , 21 , 22 , 23 ] and mechanistic [ 8 , 9 , 14 , 15 , 24 ] basis of polyploid stabilization. This work in aggregate has confirmed that the specialized meiotic program differs between auto- and allopolyploids.…”

Section: Suppression Of Meiotic Defects In Polyploids In Plantsmentioning

confidence: 99%

See 2 more Smart Citations

All Ways Lead to Rome—Meiotic Stabilization Can Take Many Routes in Nascent Polyploid Plants

Gonzalo

2022

Genes

View full text Add to dashboard Cite

Newly formed polyploids often show extensive meiotic defects, resulting in aneuploid gametes, and thus reduced fertility. However, while many neopolyploids are meiotically unstable, polyploid lineages that survive in nature are generally stable and fertile; thus, those lineages that survive are those that are able to overcome these challenges. Several genes that promote polyploid stabilization are now known in plants, allowing speculation on the evolutionary origin of these meiotic adjustments. Here, I discuss results that show that meiotic stability can be achieved through the differentiation of certain alleles of certain genes between ploidies. These alleles, at least sometimes, seem to arise by novel mutation, while standing variation in either ancestral diploids or related polyploids, from which alleles can introgress, may also contribute. Growing evidence also suggests that the coevolution of multiple interacting genes has contributed to polyploid stabilization, and in allopolyploids, the return of duplicated genes to single copies (genome fractionation) may also play a role in meiotic stabilization. There is also some evidence that epigenetic regulation may be important, which can help explain why some polyploid lineages can partly stabilize quite rapidly.

show abstract

Defining autopolyploidy: Cytology, genetics, and taxonomy

Lv,

Addo Nyarko,

Ramtekey

et al. 2024

American J of Botany

View full text Add to dashboard Cite

Autopolyploidy is taxonomically defined as the presence of more than two copies of each genome within an organism or species, where the genomes present must all originate within the same species. Alternatively, “genetic” or “cytological” autopolyploidy is defined by polysomic inheritance: random pairing and segregation of the four (or more) homologous chromosomes present, with no preferential pairing partners. In this review, we provide an overview of methods used to categorize species as taxonomic and cytological autopolyploids, including both modern and obsolete cytological methods, marker‐segregation‐based and genomics methods. Subsequently, we also investigated how frequently polysomic inheritance has been reliably documented in autopolyploids. Pure or predominantly polysomic inheritance was documented in 39 of 43 putative autopolyploid species where inheritance data was available (91%) and in seven of eight synthetic autopolyploids, with several cases of more mixed inheritance within species. We found no clear cases of autopolyploids with disomic inheritance, which was likely a function of our search methodology. Interestingly, we found seven species with purely polysomic inheritance and another five species with partial or predominant polysomic inheritance that appear to be taxonomic allopolyploids. Our results suggest that observations of polysomic inheritance can lead to relabeling of taxonomically allopolyploid species as autopolyploid and highlight the need for further cytogenetic and genomic investigation into polyploid origins and inheritance types.

show abstract

Evolution of crossover interference enables stable autopolyploidy by ensuring pairwise partner connections in Arabidopsis arenosa

Cited by 57 publications

References 90 publications

Genomic and Meiotic Changes Accompanying Polyploidization

Genomic and Meiotic Changes Accompanying Polyploidization

All Ways Lead to Rome—Meiotic Stabilization Can Take Many Routes in Nascent Polyploid Plants

Defining autopolyploidy: Cytology, genetics, and taxonomy

Contact Info

Product

Resources

About