Evolution of disability in coalworkers' pneumoconiosis.

Lyons, J P; Campbell, Harry

doi:10.1136/thx.31.5.527

Cited by 14 publications

(11 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Chest X-ray is performed on all dust workers, whereas pulmonary function tests are done only in cases with findings of pneumoconiosis on X-ray images. Generally, pulmonary function worsens and respiratory symptoms occur more frequently as pneumoconiosis advances 7,8) . However, there are a small number of cases that are found to have significant pulmonary dysfunction even with mild abnormalities on chest X-ray images.…”

Section: Introductionmentioning

confidence: 99%

Relationship between Chest X-ray Findings and Pulmonary Function Tests in Dust Workers

et al. 2005

View full text Add to dashboard Cite

Occupational injuries are decreasing due to the improvement in occupational management in the workplace in recent years. However, pneumoconiosis and its complications remain important occupational diseases. Based on the report 'survey on classification for supervision of pneumoconiosis in Japan' performed in 1994, this study compared age, number of years at the job and pulmonary function tests among work types, and examined the characteristics of cases in which pulmonary function results were worse than expected from the chest X-ray findings. In the comparison among work types, mean age was higher and %VC was lower among workers exposed to silica or asbestos, and FEV1.0% appeared to be lower among silica-exposed workers. Multiple regression analysis showed that silica or asbestos-exposed work environments strongly affected %VC. Some cases showed dissociation between the X-ray findings and pulmonary function tests, which appeared to be caused by certain types of work environments. In this study, all the subjects had findings of pneumoconiosis in their chest X-ray. It is necessary to perform a longitudinal survey on pneumoconiosis-free subjects to clarify the precise association of lung function tests with chest X-ray.

show abstract

Section: Introductionmentioning

confidence: 99%

Relationship between Chest X-ray Findings and Pulmonary Function Tests in Dust Workers

et al. 2005

View full text Add to dashboard Cite

show abstract

“…A detailed description of the miners concerned and of the methods of investigation have already been given by Ryder, Lyons, Campbell, and Gough (1970) and Lyons, Ryder, Campbell, and Gough (1972), so only very brief relevant details are given here.…”

Section: Methodsmentioning

confidence: 99%

Significance of irregular opacities in the radiology of coalworkers' pneumoconiosis

Lyons¹,

Ryder²,

Campbell³

et al. 1974

Occupational and Environmental Medicine

View full text Add to dashboard Cite

. (1974). British Journal of Industrial Medicine, 31, 36-44. Significance of irregular opacities in the radiology of coalworkers' pneumoconiosis. A correlation study of ventilatory, morbid anatomical, and radiological findings in 95 deceased coal miners who suffered with simple pneumoconiosis during life was undertaken using the new ILO U/C International Classification of Radiographs of Pneumoconiosis, which now provides for the occurrence of irregular opacities in addition to the classical rounded opacities. The study was carried out with a view to ascertaining the frequency of occurrence and the significance of irregular opacities in coalworkers' pneumoconiosis. Two x-ray films with an average interval of 11 years between them were reported on,in each case. The results showed that irregular opacities amounting to category 1 or more were present in 20 % of the earlier films and in 48 % of the later ones. Exceptionally they occurred alone but were usually admixed with classical rounded opacities.

show abstract

“…Small rounded opacities of p-type were associated with more circumscribed emphysema than larger opacities (26,2 7), although irregular shadows exhibited a greater degree of emphysema, as well as a larger decrement in forced expiratory volume (FEV1) or gas transfer, than rounded ones (27,28). Radiological category of simple pneumoconiosis was less important than the occurrence of accompanying emphysema in reflecting ventilatory impairment (29). Moreover, emphysema of unspecified type, as judged by the naked eye, existed in approximately 60% of cases with small rounded opacities, but about 90% of men were affected when the opacities were small and irregular (30).…”

Section: Human Responsesmentioning

confidence: 97%

“…Furthermore, it was estimated that the prevalence then obtaining should at least be halved during the succeeding 35 years, but overall progression appeared to be greater in men with some evidence of disease at the inception of the program. [25][26][27][28][29][30][31][32][33][34] 35-44 45-54 55-59 AGE FIGURE 1. Prevalence of pneumoconiosis, as a percentage of men Xrayed, in relation to age for 30 collieries surveyed repeatedly over a period of 22 years.…”

Section: Prevalence Dust Levelsmentioning

confidence: 99%

Prevalence and pathogenesis of pneumoconiosis in coal workers.

Heppleston

1988

Environ Health Perspect

View full text Add to dashboard Cite

Dust dose and composition do not appear to account wholly for changes in the prevalence of coal workers' pneumoconiosis in Europe. In certain coal pits high progression evidently occurred with relatively low dust exposure or vice versa, whereas progression in relation to dust levels might be variable. Exceptionally high quartz concentrations occur in coal mine dust when pneumoconiosis may progress with unusual rapidity. Under such circumstances lesions resembling silicotic nodules may be found, but with the customarily lower levels of quartz the pathological features assume the form characteristic of coal workers. Morphological changes in relation to dust content of human and animal lungs, as well as cellular behavior, have not accounted completely for the epidemiological findings. Considering all the pathological evidence helps explain the pathogenesis of pneumoconiosis and vagaries of progression. The origin of progressive massive fibrosis cannot be explained simply in terms of dust burden or immunological features, and the role of an infective factor cannot be dismissed. Moreover, lipid secretion by alveolar epithelium introduces a new element that could affect the development of simple and complicated pneumoconiosis. In vitro, cytotoxicity appeared to be too variable for predictive purposes, though direct assay of fibrogenicity using the macrophage fibrogenic factor suggested that dust dose was more important than dust composition. Assessing individual susceptibility presents serious obstacles.

show abstract

Evolution of disability in coalworkers' pneumoconiosis.

Cited by 14 publications

References 15 publications

Relationship between Chest X-ray Findings and Pulmonary Function Tests in Dust Workers

Relationship between Chest X-ray Findings and Pulmonary Function Tests in Dust Workers

Significance of irregular opacities in the radiology of coalworkers' pneumoconiosis

Prevalence and pathogenesis of pneumoconiosis in coal workers.

Contact Info

Product

Resources

About