Evolution of European bat lyssaviruses.

Abstract

Forty-seven European bat lyssaviruses (EBL) and two African insectivorous bat lyssaviruses (Duvenhage viruses) were selected for a comparison to be made of their evolutionary relationships. Studies were based on direct sequencing of the PCR-amplified products of the 400 nucleotides coding for the amino terminus of the nucleoprotein. Phylogenetic relationships were analysed after bootstrap resampling using the maximum parsimony and the neighbour-joining methods. Analyses of both the nucleotide and amino acid sequences placed these viruses in three separate clusters, namely genotype 4 (Duvenhage), genotype 5 (EBL1) and genotype 6 (EBL2). Evolutionary

Lyssavirus Surveillance in Bats, Bangladesh

“…Lagos bat virus (genotype 2) and Duvenhage virus (DUVV, genotype 4) were isolated from bats in Africa ( 2 ). European bat lyssaviruses, types 1 and 2 (EBLV-1 and EBLV-2, genotypes 5 and 6, respectively) circulate in European bat populations ( 3 ). West Caucasian bat virus, a new putative lyssavirus genotype, was recently isolated from a bat in southern Europe ( 4 ).…”

Experimental infection of serotine bats (Eptesicus serotinus) with European bat lyssavirus type 1a

“…Based on molecular characterization, EBLV-1 can be divided into the sublineages 1a and 1b. Whilst the circulation of EBLV-1a has been demonstrated in many European countries, mainly in central and western Europe, sublineage 1b appears to be somewhat restricted to Spain, France and The Netherlands (Amengual et al, 1997;Davis et al, 2005). However, sporadic findings of EBLV-1b in other countries, such as Germany and Poland, suggest that there is also a wider distribution of subtype 1b (Müller et al, 2007;Smreczak et al, 2007).…”

Susceptibility of North American big brown bats (Eptesicus fuscus) to infection with European bat lyssavirus type 1

“…Both genotypes are further divided into 'a' and 'b' sublineages based on their phylogenetic relationships (Bourhy et al, 1992;Amengual et al, 1997).…”