Evolution of Evidence-Based Medicine in Stroke

Abstract

The introduction and evolution of evidence-based stroke medicine has realized major advances in our knowledge about stroke, methods of medical research, and patient outcomes that continue to complement traditional individual patient care. It is humbling to recall the state of knowledge and scientific endeavour of our forebears who were unaware of what we know now and yet pursued the highest standards for evaluating and delivering effective stroke care. The science of stroke medicine has evolved from pathophysiological theory to empirical testing. Progress has been steady, despite inevitable disappointments and cul-de-sacs, and has occasionally been punctuated by sensational breakthroughs, such as the advent of reperfusion therapies guided by imaging.

Precise diagnosis of cardiac‐cerebral vascular diseases with magnetic resonance imaging‐based nanoprobes

“…Stroke refers to sudden interruption of the blood supply to the brain or bleeding within the brain, generally including ischemic stroke and hemorrhagic stroke. Approximately one-third of stroke patients die within a year, and one-third of patients experience permanent loss of work capacity [97][98][99]. MRA technology can provide detailed and precise brain images with high sensitivity for diagnosing ischemic stroke, including identification of ischemic areas for brain damage evaluation.…”