S U M M A R YThe European Enhanced Geothermal System (EGS, formerly Hot Dry Rock, HDR) programme of Soultz-sous-Forêts is organized around three wells drilled to a depth of about 5000 m. Hydraulic stimulations were performed in the wells in 2000 (GPK2 well), 2003 (GPK3 well) and 2005 (GPK4 well). The stimulation of GPK2 induced more than 700 seismic events with a magnitude greater than 1.0. The seismicity depicts a dense, homogeneous cloud, without any apparent structure. Medium-size earthquakes represent more than 80 per cent of the cumulative seismic moment. The b-value of the Gutenberg and Richter law is larger than 1.2. The injectivity has been increased by a factor 20. These characteristics indicate that the stimulation reactivated a 3-D dense network of fractures. The stimulation of GPK3 induced only about 250 events with a magnitude greater than 1.0 but with a greater proportion of large events, up to 2.9. The hypocentres form clear structures identified as large faults, the b-value is about 0.9 and the large events (M > 2.0) account for the greater part of the cumulative seismic moment. The injectivity of the well, which was already high before the stimulation, remained unchanged. The stimulation of GPK4 was achieved in two stages. This stimulation produced even less induced events, making the interpretation difficult. The differences between the seismic response of GPK2 and GPK3 are due to the presence of large faults cut by GPK3 or in its close vicinity and reached by the injected water. Once a seismic event occurs on a fault, a sequence of earthquakes is triggered and the seismicity behaves, for a large part, independent of the injected flow rate. The stimulations also show some evidence that creeping could be a major source of deformation, if not the main one. The future EGS programme will have to drill wells in zones free of large faults to avoid poor hydraulic performance and inconvenience to the population.