Evolution of green chemistry and its multidimensional impacts: A review

Marco, Bianca Aparecida de; Rechelo, Bárbara Saú; Tótoli, Eliane Gandolpho; Kogawa, Ana Carolina; Salgado, Hérida Regina Nunes

doi:10.1016/j.jsps.2018.07.011

Cited by 307 publications

(151 citation statements)

References 63 publications

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“…Finally, the applicability of the photosensitized oxidation process in the degradation of various groups of phenolic compounds was conducted. The study focused on three stages of experiments: (1) The photodegradation experiments, (2) biodegradability, and (3) toxicity assessments.…”

Section: Resultsmentioning

confidence: 99%

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Heterogeneous Oxidation of Phenolic Compounds with Photosensitizing Catalysts Incorporated into Chitosan

et al. 2019

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The increasing amount of hazardous micropollutants in the aqueous environment has recently become a concern, especially because they are not usually included in environmental monitoring programs. There is also limited knowledge regarding their behavior in the environment and their toxicity. This paper presents results regarding the heterogeneous photosensitized oxidation of 10 phenolic compounds under visible light. All of the selected compounds are classified as pollutants of emerging concern. For the first time, the application of photosensitizing catalysts incorporated into a chitosan carrier was investigated from several points of view, namely, structure characterization, singlet oxygen generation potential, photodegradation ability, biodegradability, and toxicity assessment. It was found that compounds of different origins were degraded with high effectivity. Photoactive chitosan was stable and could be reused for at least 12 cycles without losing its photocatalytic activity. The Hammett constants for all of the degraded compounds were determined. Improved biodegradability after the treatment was achieved for almost all compounds, apart from 4-hydroxybenzoic acid, and only slightly for 2-phenylphenol. The acute toxicity was assessed using bioluminescent Vibrio fischeri bacteria, indicating lower toxicity than the parent compounds.Photosensitized oxidation is undoubtedly one of the most important photochemical methods, since it does not generate any additional pollutants [5]. Moreover, the advantage of photosensitized oxidation is the photooxidation of hard-degradable compounds by singlet oxygen generated in the presence of air and solar radiation [5][6][7], therefore, photosensitized oxidation is classified as a green chemistry process. Moreover, because the heterogeneous process is considered to leave no residue, no sludge is produced from the process. Furthermore, if the immobilized photosensitizer remains unchanged throughout the process, the photocatalyst can easily be reused.Two general mechanisms of photosensitized oxidation for such reactions are well-known as Type I, also called the radical-involving mechanism, and Type II, the singlet oxygen mechanism [8,9]. Our previous research showed that singlet oxygen could be used for water purification. For this kind of area, the immobilization of photosensitizers onto various materials (heterogeneous system) is a desirable approach due to the easy separation from the reaction mixture and the preparation for reuse. Moreover, in homogenous systems (where the photosensitizer is dissolved in a water solution), the photosensitizer undergoes photobleaching, resulting in a rapid decrease in yield. Immobilized photosensitizers exhibit the advantages of good activity, stability against photobleaching, and repeated use [10]. Immobilization of a photosensitizer is associated with a decrease in the quantum yield of singlet oxygen [8,9]. This may be due to limitations in oxygen diffusion into and from the carrier material [9]. These disadvantages can be overcome by reusi...

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Section: Resultsmentioning

confidence: 99%

“…This approach minimizes the use of hazardous substances with efficient energy applications, promoting green solar energy. Thus, green chemistry is part of the framework for sustainable development [1,2].…”

Section: Introductionmentioning

confidence: 99%

Heterogeneous Oxidation of Phenolic Compounds with Photosensitizing Catalysts Incorporated into Chitosan

et al. 2019

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“…The main theme of green chemistry is to minimize the production of toxic and hazardous substances during the synthesis and designing synthetic protocols in the direction of low risk to nature. This insists the need of exploring green and novel perspectives towards the synthesis of pharmacologically active polyheterocyclic analogues, which are yet confronting in modern drug exploration and evolution programs.…”

Section: Figurementioning

confidence: 99%

Microwave‐Assisted Synthesis and Biological Evaluation of Some New Pyrazolothiazoles via a Multicomponent Approach

et al. 2019

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A series of new pyrazolothiazole hybrids were designed and synthesized by the microwave‐assisted multicomponent reaction of thiosemicarbazide, 3‐(furan‐2‐yl)‐1‐(pyridin‐2‐yl)prop‐2‐en‐1‐one and 1‐(pyridin‐2‐yl)‐3‐(thiophen‐2‐yl)prop‐2‐en‐1‐one with substituted 2‐bromoacetophenones. Structures of all the synthesized compounds were in good agreement with their spectral (FTIR, 1H & 13C NMR, Mass) and analytical data (CHN analysis). The target compounds were screened for their in vitro cytotoxic activity by testing against human adenocarcinoma (A549), cervical cancer (HeLa), human neuroblastoma (SK−N‐SH) and human prostate cancer (DU‐145) cell lines. From the in vitro results, it was found that the compound derived from p‐ NO2 phenyl (4 h) has potent activity against HeLa cell line with IC50 value 9.97 ± 0.05 μM. Also, the compounds having p‐OCH3 phenyl (4 c), phenyl (4 i), and p‐Cl phenyl (4 j) substitutions exhibited significant activity against HeLa cell line with IC50 values 19.78 ± 0.03 μM, 18.47 ± 0.01 μM and 15.61 ± 0.06 μM respectively.

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“…With developing need towards greener approaches, the use and modification of traditional methodologies is the need of the present, and in such a circumstance, PEG might be the solvent of higher preference because of its versatile blessings as a green reaction media. Since the arrival of green chemistry, various green chemistry orientated synthetic methods have been progressed so one can synthesize a wide variety of compounds without or less environmental hazard . One such strategy which has pulled brilliant attention of researchers in the organic synthesis using benign reaction media.…”

Section: Introductionmentioning

confidence: 99%

Efficient Synthesis, Antibacterial, Antifungal, Antioxidant and Cytotoxicity Study of 2‐(2‐Hydrazineyl)thiazole Derivatives

Adole

Jagdale

et al. 2020

ChemistrySelect

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In the present investigation, an alluring green PEG‐400 mediated one‐pot synthesis of novel 2‐(2‐hydrazinyl)thiazole derivatives from 1,2,6,7‐tetrahydro‐8H‐indeno[5,4‐b]furan‐8‐one has been unveiled via a novel synthetic pathway. The application of PEG in organic reactions as a reaction media is one of the fantastic tools of green chemistry as reactions can be carried out under generous conditions limiting environmental peril and chemical waste. PEG‐400 is recognized as a low‐cost, non‐flammable, environmentally benign, recyclable, and richly available green solvent. A series of novel 2‐(2‐hydrazineyl)thiazole derivatives have been synthesized in good to excellent yield by using the green capability of PEG‐400 solvent. These newly synthesized compounds were tested for their antimicrobial and antioxidant activities. The results revealed that these compounds show good activities compared with the standard. Additionally, all the synthesized compounds exhibit negligible cytotoxicity as compared to the positive control. The structures of all novel compounds reported herein are established using FT‐IR, 1H NMR, 13C NMR, D2O exchange experiment and HRMS techniques.

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Evolution of green chemistry and its multidimensional impacts: A review

Cited by 307 publications

References 63 publications

Heterogeneous Oxidation of Phenolic Compounds with Photosensitizing Catalysts Incorporated into Chitosan

Heterogeneous Oxidation of Phenolic Compounds with Photosensitizing Catalysts Incorporated into Chitosan

Microwave‐Assisted Synthesis and Biological Evaluation of Some New Pyrazolothiazoles via a Multicomponent Approach

Efficient Synthesis, Antibacterial, Antifungal, Antioxidant and Cytotoxicity Study of 2‐(2‐Hydrazineyl)thiazole Derivatives

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