Evolution of Mapping and Anatomic Imaging of Cardiac Arrhythmias

Packer, Douglas L.

doi:10.1111/j.1540-8159.2004.00581.x

Cited by 13 publications

(12 citation statements)

References 110 publications

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“…38 Within the border zone of the scar, abnormal myocardial fibrils are interspersed among fibrotic tissue, causing electrical activity to proceed in a slow and roundabout manner. [44][45][46] Every time the catheter touches the endocardium, the exact catheter tip position within the 3D model, as well as the local uni-or bipolar EGMs including voltage and local activation time (compared with a reference point), is recorded and added to the map. [39][40][41] To facilitate catheter ablation, real-time electroanatomical maps are created using 3D mapping systems (i.e., Carto 3D Mapping System, Biosense Webster, Diamond Bar, CA; EnSite NavX, St. Jude Medical, Inc., Saint Paul, MN) 42,43 These systems allow for exact localization and orientation of the catheter tip inside a virtual 3D reconstruction of the ventricular cavities.…”

Section: Mappingmentioning

confidence: 99%

Ventricular Tachycardia Ablation

Mittnacht

Dukkipati

Mahajan³

2015

Anesthesia &Amp; Analgesia

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Percutaneous catheter ablation is being increasingly performed in patients with recurrent ventricular tachycardia (VT) unresponsive to medical treatment. Optimal management of patients requires careful consideration of the severity of the underlying cardiac disease, the anesthetic drug interactions, and the procedural technique during VT mapping and ablation. The goal is to choose an anesthetic technique that has the least effect on arrhythmogenicity, allowing reproducibility of the VT in the electrophysiology laboratory. Anesthetics can alter action potential and ventricular depolarization directly through their effects on ion channels and gap junctions, as well as indirectly via their effects on the autonomic nervous system. Furthermore, maintaining hemodynamic stability and monitoring for adequate end-organ perfusion are additional challenges. In this review, we provide a comprehensive update on the currently performed VT ablation procedures and their anesthetic considerations.

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Section: Mappingmentioning

confidence: 99%

Ventricular Tachycardia Ablation

Mittnacht

Dukkipati

Mahajan³

2015

Anesthesia &Amp; Analgesia

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“…The present available electrophysiological models, ranging from single cell (Noble & Rudy, 2001; ten Tusscher et al 2004; Fenton et al 2005; ten Tusscher & Panfilov 2006) to tissue level (Henriquez & Papazoglou 1996; Pollard & Barr, 1991; Pollard et al 1993) and organ level (Noble, 2004, 2007; Trayanova, 2006; Vigmond et al 2008 a ), have proved sufficiently accurate to model complex processes, including ion kinetics in healthy and pathological conditions. In many cases, cardiac modelling can be used to investigate phenomena such as drug effects on the electromechanical response and arrhythmogenesis (Henriquez & Papazoglou, 1996; Packer, 2004; Rodriguez et al 2005), which are difficult to study in vivo .…”

Section: Electrophysiological Analysismentioning

confidence: 99%

Computational cardiac atlases: from patient to population and back

Young

Frangi

2009

Experimental Physiology

124

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Integrative models of cardiac physiology are important for understanding disease and planning intervention. Multimodal cardiovascular imaging plays an important role in defining the computational domain, the boundary/initial conditions, and tissue function and properties. Computational models can then be personalized through information derived from in vivo and, when possible, non-invasive images. Efforts are now established to provide Web-accessible structural and functional atlases of the normal and pathological heart for clinical, research and educational purposes. Efficient and robust statistical representations of cardiac morphology and morphodynamics can thereby be obtained, enabling quantitative analysis of images based on such representations. Statistical models of shape and appearance can be built automatically from large populations of image datasets by minimizing manual intervention and data collection. These methods facilitate statistical analysis of regional heart shape and wall motion characteristics across population groups, via the application of parametric mathematical modelling tools. These parametric modelling tools and associated ontological schema also facilitate data fusion between different imaging protocols and modalities as well as other data sources. Statistical priors can also be used to support cardiac image analysis with applications to advanced quantification and subject-specific simulations of computational physiology.

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“…This limitation has provided the incentive for the development of computer‐based mapping that chronicles both the temporal and spatial characteristics of cardiac activation. This development has also been driven by the need for increasing accuracy in arrhythmia localization as required for catheter ablation 1 …”

Section: Introductionmentioning

confidence: 99%

Evolution of Mapping and Anatomic Imaging of Cardiac Arrhythmias

Cited by 13 publications

References 110 publications

Ventricular Tachycardia Ablation

Ventricular Tachycardia Ablation

Computational cardiac atlases: from patient to population and back

Three‐Dimensional Mapping in Interventional Electrophysiology: Techniques and Technology

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