Evolution of new characters after whole genome duplications: Insights from amphioxus

Holland, Linda Z.

doi:10.1016/j.semcdb.2012.12.007

Cited by 42 publications

(35 citation statements)

References 95 publications

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“…It has long been suspected that rare, large-scale genomic rearrangements and genome-wide duplications in stem vertebrates played a key role in elaborating the vertebrate body plan 54,63-65 and increasing vertebrate complexity 66,67 . The presence of multiple homologous Hox clusters and conserved syntenic paralogy regions among jawed vertebrate chromosomes are usually taken to support the contention that there were two rounds of genome duplication during early vertebrate evolution 66 .…”

Section: A Role For Gene Duplications In Early Neural Crest Evolutionmentioning

confidence: 99%

Evolution of vertebrates as viewed from the crest

Green

Simões-Costa

Bronner‐Fraser

2015

Nature

194

174

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The origin of vertebrates was accompanied by the advent of a novel cell type: the neural crest. Emerging from the central nervous system, these cells migrate to diverse locations and differentiate into numerous derivatives. By coupling morphological and gene regulatory information from vertebrates and other chordates, we describe how addition of the neural crest specification program may have enabled cells at the neural plate border to acquire multipotency and migratory ability. Analyzing the topology of the neural crest gene regulatory network can serve as a useful template for understanding vertebrate evolution, including elaboration of neural crest derivatives.

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Section: A Role For Gene Duplications In Early Neural Crest Evolutionmentioning

confidence: 99%

Evolution of vertebrates as viewed from the crest

Green

Simões-Costa

Bronner‐Fraser

2015

Nature

194

174

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“…Although the head and brain are poorly developed in amphioxus [99][100][101][102], many genes in amphioxus are expressed in the brain in lamprey and other vertebrates [100,102,103]. It appears that these genes were important in the evolution of the brain during the transition from amphioxus to lamprey [100][101][102]. It is tempting to speculate that transcriptional regulation of the SR in an ancestral amphioxus by Δ 5 -androstenediol, 5α-androstanediol, 27-hydroxycholesterol, or paraestrol A, as well as by E2, was important in brain evolution [79,80], which would place the origins of responses to estrogens in the brain as contemporary with its reproductive actions.…”

Section: Er and Erβ Are Expression In The Brain: Transcriptional Actmentioning

confidence: 99%

The promiscuous estrogen receptor: evolution of physiological estrogens and response to phytochemicals and endocrine disruptors

Baker¹,

Lathe²

2017

Preprint

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Many actions of estradiol (E2), the principal physiological estrogen in vertebrates, are mediated by estrogen receptor-α (ERα) and ERβ. An important physiological feature of vertebrate ERs is their promiscuous response to several physiological steroids, including estradiol (E2), Δ 5 -androstenediol, 5α-androstanediol, and 27-hydroxycholesterol. A novel structural characteristic of Δ 5 -androstenediol, 5α-androstanediol, and 27-hydroxycholesterol is the presence of a C19 methyl group, which precludes the presence of an aromatic A ring with a C3 phenolic group that is a defining property of E2. The structural diversity of these estrogens can explain the response of the ER to synthetic chemicals such as bisphenol A and DDT, which disrupt estrogen physiology in vertebrates, and the estrogenic activity of a variety of plant-derived chemicals such as genistein, coumestrol, and resveratrol. Diversity in the A ring of physiological estrogens also expands potential structures of industrial chemicals that can act as endocrine disruptors. Compared to E2, synthesis of 27-hydroxycholesterol and Δ 5 -androstenediol is simpler, leading us, based on parsimony, to propose that one or both of these steroids or a related metabolite was a physiological estrogen early in the evolution of the ER, with E2 assuming this role later as the canonical estrogen.In addition to the well-studied role of the ER in reproductive physiology, the ER also is an important transcription factor in non-reproductive tissues such as the cardiovascular system, kidney, bone, and brain.

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“…Much has been speculated about the long term evolutionary consequences of genome duplications, including long-standing discussions on the evolution and origin of our own lineage, the vertebrates, and the complex body plan and diverse ecological adaptations that are hallmarks of this animal group (Freeling et al, 2015;Glasauer and Neuhauss, 2014;Holland, 2013;Ohno, 1970;Semon and Wolfe, 2007). However, it has been argued that there does not appear to be an association between genome duplication and teleost diversification (Clarke et al, 2016).…”

Section: Implications For Future Studies On Genome Evolutionmentioning

confidence: 99%

The house spider genome reveals an ancient whole-genome duplication during arachnid evolution

Schwager

Sharma

Clarke

et al. 2017

Preprint

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Background: The duplication of genes can occur through various mechanisms and is thought to make a major contribution to the evolutionary diversification of organisms. There is increasing evidence for a large-scale duplication of genes in some chelicerate lineages including two rounds of whole genome duplication (WGD) in horseshoe crabs. To investigate this further, we sequenced and analyzed the genome of the common house spider Parasteatoda tepidariorum.

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Evolution of new characters after whole genome duplications: Insights from amphioxus

Cited by 42 publications

References 95 publications

Evolution of vertebrates as viewed from the crest

Evolution of vertebrates as viewed from the crest

The promiscuous estrogen receptor: evolution of physiological estrogens and response to phytochemicals and endocrine disruptors

The house spider genome reveals an ancient whole-genome duplication during arachnid evolution

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