Evolution of self‐perceived swallowing function, tongue strength and swallow‐related quality of life during radiotherapy in head and neck cancer patients

Steen, Leen Van den; Gestel, Dirk Van; Vanderveken, Olivier M.; Vanderwegen, Jan; Lazarus, Cathy L.; Daisne, Jean-François; Laer, C. Van; Specenier, Pol; Rompaey, Diane Van; Mariën, Steven; Lawson, Georges; Chantrain, Gilbert; Desuter, Gauthier; Weyngaert, D. Van den; Cvilic, Sophie; Beauvois, Sylvie; Allouche, Johan; Delacroix, Laurence; Vermorken, Jan B.; Peeters, Marc; Dragan, Tatiana; Heyning, Paul Van de; Bodt, Marc De; Nuffelen, Gwen Van

doi:10.1002/hed.25684

Cited by 16 publications

(17 citation statements)

References 66 publications

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“…As the tongue consists of types I and II muscle fibers, 18 with type II muscle fibers being sensitive to early RT injury, 9 it can be assumed that TS will be affected by RT. It was confirmed that general reduced strength in HNC musculature follows RT, 1,19 with one recent publication 5 describing significant reductions in isometric TS (maximal isometric pressure [MIP]) and TS during swallowing (Pswal) already during RT.…”

Section: Introductionmentioning

confidence: 56%

“…It is a serious and disabling complication, resulting in impaired nutrition, aspiration pneumonia, and impaired quality of life (QoL). [3][4][5][6] These outcomes are life threatening and are exhausting the healthcare resources. 3,7,8 RAD can have its onset during therapy or even weeks to months following treatment due to the RT-induced, never-ending cascade of tissue fibrosis and muscle atrophy.…”

Section: Introductionmentioning

confidence: 99%

“…Radiation‐associated dysphagia (RAD) is one of the most prevalent acute and late toxicities after radiotherapy 2 (RT) and concomitant chemoradiotherapy 3 (CCRT). It is a serious and disabling complication, resulting in impaired nutrition, aspiration pneumonia, and impaired quality of life (QoL) 3‐6 . These outcomes are life threatening and are exhausting the healthcare resources 3,7,8 .…”

Section: Introductionmentioning

confidence: 99%

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Effect of tongue‐strengthening exercises on tongue strength and swallowing‐related parameters in chronic radiation‐associated dysphagia

et al. 2020

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Background Radiation‐associated dysphagia (RAD) is highly prevalent in head and neck cancer (HNC) patients, with insufficient tongue strength (TS) as a characteristic of this disabling complication. The effects of tongue‐strengthening exercises (TSE) on TS, swallowing, and quality of life (QoL) have not been studied in this population. Methods A prospective phase 2 study using an 8 weeks during TSE protocol was carried out in 15 patients with chronic RAD. Outcome parameters were maximal isometric pressure (MIP), TS during swallowing (Pswal), swallowing function, and QoL. All parameters were evaluated at baseline, after 4 and 8 weeks of training, and 4 weeks after the last training session. Results MIP increased significantly, without detraining effects. Pswal did not increase significantly, but relevant effect sizes were measured. Swallowing function ameliorated, but did not result in increased functional oral intake, self‐reported outcome or QoL. Conclusion TSE in patients with RAD results in increased strength and swallowing function.

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Section: Introductionmentioning

confidence: 56%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Effect of tongue‐strengthening exercises on tongue strength and swallowing‐related parameters in chronic radiation‐associated dysphagia

et al. 2020

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“…Studies have highlighted the importance of long-term swallowing and voice impairment, with a small number of studies specifically focusing on these issues [1][2][3][4][5][6]. Especially swallowing is strongly associated with impaired quality of life, which has been demonstrated in several studies [7][8][9]. Moreover, dysphagia and pain are independent risk factors for worse survival [10][11][12][13][14].…”

Section: Introductionmentioning

confidence: 99%

Course of Self-Reported Dysphagia, Voice Impairment and Pain in Head and Neck Cancer Survivors

Zebralla

Wiegand

Dietz

et al. 2021

Biology

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Background: Head and neck cancer (HNC)-specific symptoms have a substantial impact on health-related quality of life. The aim of this study was to determine whether self-reported dysphagia, voice problems and pain of HNC patients changed over time and whether specific clinical or sociodemographic variables were associated with these symptoms. Methods: HNC patients (n = 299) in an outpatient setting answered questionnaires (Eating Assessment Tool-10; questions from the EORTC QLQ-C30 and EORTC H&N35) on dysphagia, voice problems and pain, collected with the software “OncoFunction” at three different timepoints (t1–t3) after diagnosis. The mean score changes from t1 to t3 were expressed in terms of effect sizes d. The impact of sociodemographic and clinical factors on the course of the variables was tested with multivariate analyses of variance. Results: Dysphagia, voice impairment and pain in HNC survivors significantly improved over a period of approximately 14 months after diagnosis. Tumor site, stage, treatment modality, occupational state and ECOG state were significantly correlated with self-reported functional outcome. The pain level of the HNC patients was rather low. Conclusions: Patients suffer from functional impairments after HNC treatment, but an improvement in self-reported symptoms could be demonstrated within this time period.

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“… 2 , 3 The prevalence of dysphagia After Parkinson is estimated to vary from 11% to 87%. 4 , 5 Between 31% and 79% of head and neck cancer patients experience dysphagia followed radiotherapy, 6 , 7 and 8%–80% of patients with stroke experience swallowing disorders. 8 Dysphagia is a major cause of mortality and morbidity due to life-threatening complications, including dehydration, malnutrition, and aspiration pneumonia.…”

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confidence: 99%

Effects of Transcutaneous Neuromuscular Electrical Stimulation on Swallowing Disorders

Sun

Chen

Qiao

et al. 2020

Am J Phys Med Rehabil

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Evolution of self‐perceived swallowing function, tongue strength and swallow‐related quality of life during radiotherapy in head and neck cancer patients

Cited by 16 publications

References 66 publications

Effect of tongue‐strengthening exercises on tongue strength and swallowing‐related parameters in chronic radiation‐associated dysphagia

Effect of tongue‐strengthening exercises on tongue strength and swallowing‐related parameters in chronic radiation‐associated dysphagia

Course of Self-Reported Dysphagia, Voice Impairment and Pain in Head and Neck Cancer Survivors

Effects of Transcutaneous Neuromuscular Electrical Stimulation on Swallowing Disorders

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