Orogenic topography results from the complex processes imposed by climate, tectonics, and their feedbacks mainly through river incision (e.g., Champagnac et al., 2012;Whipple, 2004). In this context, fluvial topography and exhumation rate histories can provide an archive of climatic (e.g., Bender et al., 2020) and tectonic (e.g., Schildgen et al., 2007) changes with time. As fluvial topography evolves over geological time, the control it exerts on erosion would also change with time (e.g., Champagnac et al., 2012), but how the control changes through time remains ambiguous. The Tibetan Plateau is the highest plateau on Earth and is characterized by high topographic relief at its margins (Montgomery & Brandon, 2002;Yin, 2006) formed through river incision (Figure 1) and these rivers are expected to be very sensitive to climate and tectonic changes (e.g., Nie et al., 2018). There are several large river drainages including the Yangtze, Mekong, Salween, and Yarlung across the southern and southeastern Tibetan Plateau and Himalayas (Figure 1). Their unusual geometries and topographies have been considered to be the result of tectonic deformation and drainage reorganization (e.g., Wang, Scherler, et al., 2014;Zhang et al., 2019), as well as climate change (e.g., Nie et al., 2018). Therefore, rivers in the Tibetan Plateau and the Himalayas are natural laboratories to investigate the complex links among tectonics, climate, surface process, and drainage reorganization.The west-to-east flowing Yarlung River, located within the Indian-Asian Collision Zone (IACZ, including the Gangdese arc, the Yarlung Zangbo Suture Zone, and the Tethyan Himalaya), is one of the largest rivers that flows from the Tibetan Plateau (Figures 1 and 2). Its source is high in southern Tibet and the Yarlung River cuts through the eastern syntaxis before flowing through Siang River into the Brahmaputra River.