2009
DOI: 10.1016/j.jamcollsurg.2008.10.014
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Evolving Preoperative Evaluation of Patients with Pancreatic Cancer: Does Laparoscopy Have a Role in the Current Era?

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Cited by 83 publications
(47 citation statements)
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“…Other recent studies showed similar results with high accuracy for the assessment of arterial invasion for CT and even for MRI using latest generation devices [10,25,26]. These improvements help to increase the rate of correct indications for and successful completions of open surgery with curative intent in pancreatic cancer patients [27]. However, despite the improvements of imaging in this respect, its remaining inaccuracy regarding arterial involvement demands surgical exploration, at least in equivocal cases, as this is still the gold standard in determining resectability.…”
Section: Arteriessupporting
confidence: 55%
“…Other recent studies showed similar results with high accuracy for the assessment of arterial invasion for CT and even for MRI using latest generation devices [10,25,26]. These improvements help to increase the rate of correct indications for and successful completions of open surgery with curative intent in pancreatic cancer patients [27]. However, despite the improvements of imaging in this respect, its remaining inaccuracy regarding arterial involvement demands surgical exploration, at least in equivocal cases, as this is still the gold standard in determining resectability.…”
Section: Arteriessupporting
confidence: 55%
“…Liu and Mayo (3,4) reported the finding of occult tumor during staging laparoscopy in 34% and 27.6% of the patients, respectively.…”
Section: Discussionmentioning
confidence: 99%
“…12 In patients who have large tumors, especially in the body and tail of the pancreas, as well other indications of advanced disease such as weight loss, an elevated level of carbohydrate antigen 19-9 (CA 19-9), ascites, or equivocal CT findings, a staging laparoscopy can accurately determine metastatic and vascular involvement. 13 CA 19-9 is the only biomarker with demonstrated clinical usefulness and is useful for therapeutic monitoring and early detection of recurrent disease after treatment in patients with known pancreatic cancer. 14e16 However, CA 19-9 is not a specific biomarker for pancreatic cancer; its level may be elevated in other conditions such as cholestasis.…”
Section: Discussionmentioning
confidence: 99%