Evolving Technologies in the Treatment of Cerebral Aneurysms

Vargas, Jan; Starke, Robert M.; Spiotta, Alejandro M; Turner, Raymond D

doi:10.1016/b978-0-12-811740-8.00020-4

Cited by 1 publication

(1 citation statement)

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“…The guiding principle of cerebral aneurysm treatments is to reduce the hemodynamic loading on the arterial wall to prevent rupture and further dilation. Often Guglielmi detachable coils 13 are used for the endovascular embolization procedure. Dislocation, compaction, and inflammation are some of the complications associated with the coiling procedure.…”

Section: Introductionmentioning

confidence: 99%

Assessment and visualization of hemodynamic loading in aneurysm sac and neck: Effect of foam insertion

Pandey

Paul

Das

et al. 2021

Proc Inst Mech Eng H

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Shape memory polymer (SMP) foam is often proposed as the future alternative of coils in aneurysm treatment devices. Present work numerically investigates the unsteady, three-dimensional simulation of blood flow in a cerebral aneurysm filled with SMP foam. Simulations are conducted on patient-specific geometries with realistic blood velocity waveform imposed at the inlet while SMP foam is treated as a porous medium. The present study introduces a “loading risk map” that helps to visualize the hemodynamic effect of foam insertion on the aneurysm sac and neck. The loading risk maps suggest that while the SMP foam subdues the flow and wall shear pulsations in the aneurysm sac, the pressure distribution is minimally affected. The maps suggest that while the downstream lip is the most risk-prone site for both geometries, downstream vascular anatomy significantly influences foam efficiency in reducing pressure and wall shear stress loading.

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Section: Introductionmentioning

confidence: 99%