Ewing′s sarcoma of the mandible

Sharada, P; Girish, H. C.; Umadevi, H S; Priya, NS

doi:10.4103/0973-029x.37800

Cited by 15 publications

(18 citation statements)

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“…47-49 Vincristine, doxorubicin, cyclophosphamide, ifosfamide, and actinomycin-D are the most widely used anticancer agents for definitive chemotherapy. 5051 Demanding function and esthetic reconstruction efforts are usually required for maintaining an acceptable quality of life.…”

Section: Discussionmentioning

confidence: 99%

Ewing\'s Sarcoma of Mandible: An Impressive Case of Spontaneous Mandible Regeneration

Chatzistefanou

Kabesi

Paraskevopoulos

et al. 2016

International Journal of Clinical Pediatric Dentistry

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Ewing’s sarcoma (ES) is an uncommon aggressive bone malignancy that mainly affects children and adolescents. Mandible involvement is quite rare and usually represents metastasis from another skeletal site. Combined therapy including wide surgical resection and preoperative and postoperative chemotherapy has been demonstrated as the mainstay of therapeutic approach. As improved therapeutic modalities have significantly increased survival over the last decades, functional and esthetic reconstruction of the postmandibulectomy defect is usually necessary for patient’s total rehabilitation. We report a case of ES of the mandible with special consideration to the postresection spontaneous structural and functional regeneration of the mandible.How to cite this articleChatzistefanou I, Kabesi S, Paraskevopoulos K, Koliouskas D, Antoniades K. Ewing’s Sarcoma of Mandible: An Impressive Case of Spontaneous Mandible Regeneration. Int J Clin Pediatr Dent 2016;9(3):273-277.

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Section: Discussionmentioning

confidence: 99%

Ewing\'s Sarcoma of Mandible: An Impressive Case of Spontaneous Mandible Regeneration

Chatzistefanou

Kabesi

Paraskevopoulos

et al. 2016

International Journal of Clinical Pediatric Dentistry

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“…The tumors showed male preponderance and commonly affected mandible. [10] Sidhu in 1976 and Narasimhan in 1993 reported cases of ES affecting mandible and zygoma, respectively. [911] In 2003, Singh described involvement of mandible whereas in 2006 Sharada reported involvement of both the jaws.…”

Section: Discussionmentioning

confidence: 99%

Ewing′s sarcoma of mandible: A case report and review of Indian literature

et al. 2012

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Ewing's sarcoma (ES) is a rare malignancy primarily affecting skeletal system and it is commonly diagnosed in children and young adults. It seldom occurs in the head and neck region. ES has poor prognosis because of uncontrolled metastatic potential making early diagnosis and intervention critical for survival of the patient. This paper reports a rare case of ES involving mandible in an 8-year-old girl with clinical, radiological, histopathological and immunohistochemical features.

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“…6 Facial skeletal quite rare with mandible being the most commonly affected bone. 2 Approximately 90% of the reported cases occurring in the mandible have been primary lesions and 10% have been metastases. 7 It is mostly seen in patients younger than 20 years (80%).…”

Section: Case Reportmentioning

confidence: 99%

“…1 Ewing's sarcoma is genetically and histologically distinctive small round cell sarcoma of bone, and it constitutes 1% of all malignant tumors in children. 2 It is a notoriously aggressive and destructive malignancy of bone arising from marrow mesenchymal stem cells. Since then, it has been documented as a distinct malignancy of primitive mesenchymal stem cells that have undergone a unique reciprocal translocation of chromosomes 11 and 22.…”

Section: Introductionmentioning

confidence: 99%

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