Ewing Sarcoma Family of Tumors

Abstract

The diagnosis and management of Ewing sarcoma is laborious and requires the correlation of multiple imaging modalities. This is an aggressive, malignant tumor of bone and soft tissue. Ewing sarcoma rarely affects individuals older than 20 years of age. Clinical symptoms are variable and nonspecific. Biopsy is the only definitive diagnosis. Multimodality medical imaging plays a great role in visualizing the tumor, documenting metastatic spread, tumor staging, associated complications, and response to therapy. Standard treatment of Ewing sarcoma is a multimodal therapeutic regimen, including chemotherapy, surgery, and radiation. Prognosis depends on tumor location, presence of metastases, and tumor size.