Ex vivo mechanical properties of a 2.5‐mm bone anchor for treatment of cranial cruciate ligament rupture in toy breed dogs

Roca, Rodrigo; Peura, Aliisa; Kowaleski, Michael P.; Watson, Mallory T.; Lendhey, Matin; Rocheleau, P. J.; Hulse, Donald A.

doi:10.1111/vsu.13399

Cited by 7 publications

(11 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…We achieved to 3D print scaffolds, named EtOH75_HA and THF75_HA, with different geometry, microstructure, mechanical properties, and osteoconductivity by tuning PVB solvent. This proof-of-concept study further widens the way to produce next-generation bone scaffolds with tuned mechanical properties, porosity, shape, and HA deposition, which endorse bone regeneration and homeostasis in different anatomic bone locations, such as trabecular bone [71], or calvaria bone [72][73][74][75][76].…”

Section: Discussionmentioning

confidence: 99%

Biofabrication of 3D printed hydroxyapatite composite scaffolds for bone regeneration

et al. 2021

View full text Add to dashboard Cite

Biofabrication has been adapted in engineering patient-specific biosynthetic grafts for bone regeneration. Herein, we developed a three-dimensional (3D) high-resolution, room-temperature printing approach to fabricate osteoconductive scaffolds using calcium phosphate cement (CPC). The non-aqueous CPC bioinks were composed of tetracalcium phosphate, dicalcium phosphate anhydrous, and Polyvinyl butyral (PVB) dissolved in either ethanol (EtOH) or tetrahydrofuran (THF). They were printed in an aqueous sodium phosphate bath, which performs as a hardening accelerator for hydroxyapatite formation and as a retainer for 3D microstructure. The PVB solvents, EtOH or THF, affected differently the slurry rheological properties, scaffold microstructure, mechanical properties, and osteoconductivity. Our proposed approach overcomes limitations of conventional fabrication methods, which require high-temperature (>50 °C), low-resolution (>400 μm) printing with an inadequate amount of large ceramic particles (>35 μm). This proof-of-concept study opens venues in engineering high-resolution, implantable, and osteoconductive scaffolds with predetermined properties for bone regeneration.

show abstract

Section: Discussionmentioning

confidence: 99%

Biofabrication of 3D printed hydroxyapatite composite scaffolds for bone regeneration

et al. 2021

View full text Add to dashboard Cite

show abstract

“…Bone anchors have been used in vivo and ex vivo in the shoulder, stifle, coxofemoral and tarsal joint for treatment of joint luxations or ligament/tendon avulsions and ruptures but not reported in the elbow 15,28–31 . Clinical application of bone anchors (IMEX Veterinary, Arthrex) was straightforward and uncomplicated in the three cases described here.…”

Section: Discussionmentioning

confidence: 90%

Use of bone anchors for the treatment of partial and complete traumatic elbow luxations: A retrospective case series of three dogs

Logothetou¹,

Pappa

Pettitt

et al. 2022

Vet Record Case Reports

View full text Add to dashboard Cite

Three dogs presented with traumatic lateral elbow luxation following road traffic accidents. Concurrent injuries included skin abrasions and coxofemoral luxation. All luxations were reduced and stabilised with bone anchors through a lateral approach to the elbow joint and had an augmented or prosthetic lateral collateral ligament placed. One elbow joint was stabilised with FASTak anchor (Arthrex, Karsfeld, Germany) and two with suture anchors by IMEX bone anchor (Veterinary, Longview, TX). Reluxation occurred in one case 24 hours after discharge requiring revision surgery. Median followup time for the three cases was 180 days (range: 49-2920) and the functional outcome was considered excellent in all cases as determined by veterinary assessment, clinical record reviews, owner communication and Liverpool Osteoarthritis in Dogs (LOAD) questionnaire. In conclusion, placement of bone anchors with augmentation of the lateral collateral ligament for management of traumatic elbow luxation in dogs is a good alternative to previously reported surgical techniques.

show abstract

“…Specimens were covered in a salinesoaked cloth and stored in a deep freezer at -20 °C. 25 Before performing the biomechanical testing, specimens were left at room temperature to thaw for 2 hours. The 12 femurs had both sutures placed in the opposite side and were randomly assigned to having an FFLS or BAS placed on either the lateral or medial aspect of the femur.…”

Section: Bone Modelmentioning

confidence: 99%

“…The femurs were oriented at a 70° angle relative to the base of the machine, and the load bar was positioned to apply the load on the suture loop at an angle of 150°. 25 The positioning of the femurs was based on a previous canine study 25,27,28 that defined the orientation of the femur and the constructs associated with a dog in the stance phase of locomotion (Figure 2).…”

Section: Positioningmentioning

confidence: 99%

Ex vivo biomechanical evaluation and comparison of lateral femoro-fabella ligament suture and lateral suture with bone anchor for cranial cruciate ligament repair in cats

Tassani,

de Witt,

Fosgate

et al. 2024

ajvr

View full text Add to dashboard Cite

OBJECTIVE To compare the biomechanical properties of lateral femoro-fabella ligament suture (FFLS) and lateral suture with a bone anchor suture (BAS) for management of feline cranial cruciate ligament disease. ANIMALS 12 femurs from 6 mature cat cadavers. METHODS The samples were collected from April to June 2023. The specimens had an FFLS and, subsequently, BAS placed and were positioned into a biomechanical testing machine, preloaded from 5 N to 15 N for 100 cycles, and subsequently, a load to suture failure was applied. The displacement at 5 N and 15 N, the total precycle displacement (millimeters), the force at 3 mm displacement and at failure (newtons), the displacement at failure (millimeters), and the stiffness to failure (Newton:millimiter) were recorded. Nonparametric Wilcoxon signed-rank tests were used to compare data between the 2 groups. RESULTS The displacement at 5 N and 15 N and the total precycle displacement were significantly higher in the FFLS group compared to the BAS group. Additionally, the FFLS group results showed less consistent displacement and marked variability. The force (newtons) at 3 mm displacement was higher in the BAS group. There was no significant difference in force and no significant difference in displacement at failure between the 2 groups. However, the stiffness to failure (N/mm) was significantly higher in the BAS group. CONCLUSION BAS represented a more stable and reliable femur attachment for extracapsular suture in cats. CLINICAL RELEVANCE To demonstrate the stability and reliability between BAS and FFLS and influence implant selection in the treatment of cranial cruciate ligament rupture in cats with evaluation of biomechanical properties.

show abstract

Ex vivo mechanical properties of a 2.5‐mm bone anchor for treatment of cranial cruciate ligament rupture in toy breed dogs

Cited by 7 publications

References 27 publications

Biofabrication of 3D printed hydroxyapatite composite scaffolds for bone regeneration

Biofabrication of 3D printed hydroxyapatite composite scaffolds for bone regeneration

Use of bone anchors for the treatment of partial and complete traumatic elbow luxations: A retrospective case series of three dogs

Ex vivo biomechanical evaluation and comparison of lateral femoro-fabella ligament suture and lateral suture with bone anchor for cranial cruciate ligament repair in cats

Contact Info

Product

Resources

About