Exacerbation of Senile Macular Degeneration Following Cataract Extraction

Blair, Charles J.; Ferguson, James

doi:10.1016/0002-9394(79)90195-8

Cited by 44 publications

(24 citation statements)

References 5 publications

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“…1 Cataract surgery has also been reported to exacerbate subretinal neovascularisation in age-related macular degeneration. 8 The phenomenon has hitherto not been reported with ocular ischaemic syndrome. This may be owing to the rarity of cases as many patients with ocular ischaemic syndrome do not undergo cataract surgery owing to a poor visual prognosis in many of them, and as the condition is not in itself common.…”

Section: Discussionmentioning

confidence: 99%

Cataract surgery using phacoemulsification may reactivate angiogenic growth factors in ocular ischaemic syndrome

Zaidi

Sharkawi

Weir

et al. 2004

Eye

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Section: Discussionmentioning

confidence: 99%

Cataract surgery using phacoemulsification may reactivate angiogenic growth factors in ocular ischaemic syndrome

Zaidi

Sharkawi

Weir

et al. 2004

Eye

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“…17,21,[26][27][28] A report of post-mortem eyes published in 1994 found that neovascular AMD (nAMD) was observed more often in pseudophakic eyes than phakic eyes. 29 None of these studies were able to establish whether these findings arose prior to or after cataract surgery.…”

Section: Evidence Suggesting An Association Between Cataract Surgery mentioning

confidence: 99%

The Impact of Cataract Surgery on AMD Development and Progression

Qian

Young

2014

Seminars in Ophthalmology

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Age-related macular degeneration (AMD) and cataract are two leading causes of visual impairment worldwide which often occur concurrently in the same patient. With more than 1.6 million cataract operations performed per year in the United States, many of which occur in the nearly 1.75 million individuals diagnosed with AMD, there is ample incentive to further explore the interaction between these two conditions. Notably, the role of cataract surgery on AMD development and progression is of particular interest. This review summarizes the major findings from literature focusing on the effect of cataract surgery on AMD.

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“…Although earlier case series [6][7][8][9] and a postmortem study 10 suggested a possible association between aphakia or pseudo-phakia and late ARM, the evidence from these studies is relatively weak. Findings from large population-based studies 11,12 appeared to support an association between prior cataract surgery and an increase in late ARM prevalence.…”

Section: Introductionmentioning

confidence: 97%

“…The strongest evidence to date, came from a pooled data analysis of two large populationbased studies, 13 that showed a significantly increased 5-year incidence of late ARM (odds ratio (OR) 5.7, 95% confidence interval (CI) 2.4-13.6) in nonphakic (aphakic or pseudo-phakic) eyes compared to phakic eyes, after accounting for age, smoking, and the presence and severity of early ARM lesions at baseline. 13 The Beaver Dam Eye Study (BDES) has reported a significant association between cataract surgery performed prior to baseline and the incidence of late ARM after both [5][6][7][8][9][10][11][12][13][14] and 10-year 15 intervals. The potential for an increased late ARM risk after cataract surgery remains topical and controversial, as indicated by two recent editorials published in Archives of Ophthalmology.…”

Section: Introductionmentioning

confidence: 99%

Early age-related maculopathy in eyes after cataract surgery

Pham

Cugati

Rochtchina

et al. 2006

Eye

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Purpose To assess age-related maculopathy (ARM) in eyes of patients who had undergone cataract surgery for at least a year. Methods Consecutive patients aged 60 þ years who had undergone cataract surgery at Westmead Hospital, Sydney, Australia, during 2001-2003 were examined in 2004. Interview using standardized questionnaires and stereo retinal photography was performed. Retinal photographs were graded using the Wisconsin ARM grading system. The proportions with ARM were compared between surgical and nonsurgical eyes, and between this surgical cohort and the Blue Mountains Eye Study (BMES) population. Results Of the 622 eligible patients, 454 (73%) were re-examined, with a mean followperiod of 2.8 years. Surgical eyes had a higher proportion of early ARM compared to nonsurgical eyes (15.2 vs 10.3%, P ¼ 0.07) and to the early ARM prevalence found in BMES participants of similar age (14.5 vs 6.9%, Po0.01), which persisted after age standardization to the BMES population (9.7 vs 6.9%, Po0.05). Conclusions We found an increased prevalence of early ARM in surgical eyes of patients 1-3 years after cataract surgery. Whether this increased early ARM prevalence leads to an increased prevalence of late ARM in the long-term warrants further investigation.

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Exacerbation of Senile Macular Degeneration Following Cataract Extraction

Cited by 44 publications

References 5 publications

Cataract surgery using phacoemulsification may reactivate angiogenic growth factors in ocular ischaemic syndrome

Cataract surgery using phacoemulsification may reactivate angiogenic growth factors in ocular ischaemic syndrome

The Impact of Cataract Surgery on AMD Development and Progression

Early age-related maculopathy in eyes after cataract surgery

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