Single-layer reticulated domes are commonly used structural layouts due to their large span capacity and novel appearance. Such structures contain a large number of members, which inevitably lead to imperfection. In this study, a numerical method considering the initial curvature of members, nodal installation error, and joint stiffness was proposed. The randomness of the initial curvature direction, initial curvature magnitude, and joint stiffness could be considered simultaneously. The influence of random geometrical imperfection on the stability of two types of latticed shell structures was investigated. The proposed method could be performed based on general finite element software, and its applicability could be ensured.