Examination of Non-Modified Carbon Fibre Bundle as an Electrode for Electrochemical Sensing

Abstract

This study presents a simple and cost-effective method for producing carbon fibre microcylinder bundle (CFMB) electrodes that are highly stable and reproducible for electrochemical sensing applications. The CFMBs were integrated into a 3D-printed electrochemical cell and tested for dopamine (DA) detection. The results demonstrated a linear increase in current with increasing DA concentration, reaching a sensitivity of 428 nAμM−1 and a limit of detection (LOD) of 8.85 μM. The CFMBs also showed high electrochemical selectivity for DA due to the similar oxidation potentials of dopamine and the chemical groups present on the surface of the CFMBs. The reproducibility of the CFMBs was also demonstrated by the low variation in background currents between different electrodes. These findings highlight the potential of CFMBs as a low-cost and effective platform for electrochemical sensing applications.

Detection of Dopamine Based on Aptamer-Modified Graphene Microelectrode

“…It plays a fundamental role in transmitting messages of excitement and pleasure. Abnormal levels of DA in the body can lead to various diseases, such as Parkinson's disease, schizophrenia, Tourette syndrome, attention deficit hyperactivity disorder, and pituitary tumors, among other neurological disorders [2][3][4]. Therefore, the accurate detection of this biomolecule is crucial.…”

“…Carbon-based materials have the advantages of excellent conductivity, low cost, and high stability. Among carbon-based materials, carbon-based fiber materials have the characteristics of a large specific surface area, high flexibility, easy functionalization, good biocompatibility, and stable electrochemical performance, which provide abundant active sites for improving sensitivity and exerting an excellent electrocatalytic effect [3,21].…”