Examination Of The Occurrence Of Acute Respiratory Events During The 24 Months Prior To COPD Diagnosis

Suruki, Robert; East, Lauren; Cockle, Sarah; Toms, Mark; Sampson, Tim; Davis, Kourtney J.

doi:10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a6558

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“…They included only “lower respiratory events”. 25 At all levels of events from 0 to 3 or more in the 2 years, women were more likely to have an event as confirmed by our data. The rates of 0, 1, 2, and 3 or more events are very similar in their data and ours ( Table 2 ) again confirming that our data are representative of primary care population respiratory event rates for people with COPD.…”

Section: Discussionsupporting

confidence: 85%

“…The data from our study may be more likely to capture people with 2 or 3 events since we captured oral steroid bursts and hospitalizations that may not have the respiratory event listed among the codes which both we and Suruki included. 25 Suruki study did not collect information on post-diagnosis events. In our data, the rate of any event and lower respiratory events was higher in the post-diagnosis period compared with the prediagnosis period in the same group of individuals.…”

Section: Discussionmentioning

confidence: 99%

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Exacerbations in the pre- and post-COPD diagnosis periods

Yawn

Wollan

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2013

POR

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PurposeChronic obstructive pulmonary disease (COPD) is usually recognized in its later stages, delaying therapeutic opportunities. Screening questionnaires have modest sensitivities and specificities. Adding questions about prior respiratory events might improve screening characteristics.MethodsUsing administrative data from all health care facilities in Olmsted County, Minnesota USA, we identified all adults with an initial diagnosis of COPD from 2005 through 2007. For each individual we identified all coded lower and upper respiratory events in the 2 years before and the 2 years after the COPD diagnosis and categorized them as probable or possible COPD exacerbations.Results356 women and 346 men (N = 702) with a mean age of 67.5 years and 66.6 years respectively had a first diagnosis of COPD during the study period. Respiratory events in the 2 years prior to a COPD diagnosis were common with a range of 0 to 16 events per individual and a mean (SD) of 2.04 (2.14), 1.38 (1.86) all of which were probable COPD exacerbations. Prediagnostic respiratory events were predictive of similar events in the post diagnostic period (odds ratio = 1.6, 95% confidence interval [CI] 1.3 to 1.8).ConclusionInquiring about the number and type of upper or lower respiratory events in the 2 past years may be a useful addition to the “screening” criteria to improve COPD identification, especially those at risk of frequent exacerbations.

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Section: Discussionsupporting

confidence: 85%

Section: Discussionmentioning

confidence: 99%