Protestors recently repurposed the abortion rights’ mantra, “my body, my choice,” to oppose COVID-19 mandates. But do those who oppose public health mandates fully support the right to choose? We answer this question by using exploratory analyses to identify the unique response patterns underlying support for abortion and COVID-19 mandates in random samples from the United States (Study 1; N = 2,331) and New Zealand (Study 2; N = 33,310). Latent profile analyses revealed a small subgroup in both countries (12.6% and 3.4% of the respective samples) who opposed mandates. Yet contrary to the “my body, my choice” rhetoric seen at anti-mandate protests, they also opposed abortion. Across both studies, those in the Anti-Mandate profile tended to be more religious, conservative, and distrustful of institutions. In Study 2, they were also low on cognitive consistency and high on conspiracy belief. Finally, the Anti-Mandate profile was opposed to free speech critical of both the United States and religion (Study 1), high on sexual prejudice (both studies), unsupportive of progressive protests (but supportive of reactionary protests; Study 2), and likely to vote for conservative parties (both studies). These results reveal the mobilization potential of the anti-mandate movement, uncover important contradictions within its members, and illustrate the nuanced ways in which opposition to gender policies (i.e., reproductive rights) coalesce with reactionary protests.