Since new implausible conspiracy theories emerge frequently and are thought to have detrimental effects on individuals and society (e.g., vaccine hesitancy, prejudice, and worse interpersonal relationships), developing effective interventions to reduce conspiracy beliefs is urgent. The present Bayesian three-level meta-analysis with 273 effect sizes from 56 independent samples (N = 27,996) provides the first comprehensive overview of factors affecting intervention effectiveness, including characteristics of samples, interventions, and conspiracy beliefs. The findings indicate that interventions tend to be moderately effective (g = 0.16, 95% CR [0.12, 0.20]). However, effect sizes exhibited substantial variability. By adopting evidence-based recommendations, such as tailoring intervention content to the outcome content and avoiding single-item measures of conspiracy beliefs, intervention effectiveness can be enhanced to g = 0.3 or higher. Furthermore, the identified research gaps, such as the scarcity of research on long-term effects, provide valuable insights for further improvements in this research area.