2023
DOI: 10.1002/aws2.1327
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Examining the efficacy of copper‐silver ionization for management of Legionella: Recommendations for optimal use

Abstract: Although copper‐silver ionization (CSI) has been used for 30 years to inactivate Legionella bacteria and other opportunistic pathogens in water, the literature is a mix of both successes and failures. This paper reviews the technology and case studies to help improve the success of CSI installations. Important is a properly designed system capable of consistent delivery of copper/silver ions at their target levels. However, even the most advanced system will fail if not properly operated and maintained. Water … Show more

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Cited by 5 publications
(3 citation statements)
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“…Another is that copper and silver ion concentration fluctuations lead to insufficient inactivation of L. pneumophila allowing for regrowth. 54 To date, the mechanism(s) underlying silver ion resistance in many DWPIs is unknown. Possible non-specific heavy metal efflux pumps, similar to that seen for copper resistance, 56 could be present within L. pneumophila and other DWPIs.…”
Section: Microbiology Considerations Underlining the Efficacy And Eva...mentioning
confidence: 99%
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“…Another is that copper and silver ion concentration fluctuations lead to insufficient inactivation of L. pneumophila allowing for regrowth. 54 To date, the mechanism(s) underlying silver ion resistance in many DWPIs is unknown. Possible non-specific heavy metal efflux pumps, similar to that seen for copper resistance, 56 could be present within L. pneumophila and other DWPIs.…”
Section: Microbiology Considerations Underlining the Efficacy And Eva...mentioning
confidence: 99%
“…51 However, studies on CSI report an initial decrease followed by an increase in the number of culturable Legionella (over varying time periods) before returning to pre-installation concentrations. 52 One explanation for this observation is the emergence of resistance due to consistent, sub-lethal exposure to copper and silver 53 (sub-lethal due to poor transport through biofilms, 54 poor building plumbing hydraulics, 55 or pH influences on ion release). Another is that copper and silver ion concentration fluctuations lead to insufficient inactivation of L. pneumophila allowing for regrowth.…”
Section: Microbiology Considerations Underlining the Efficacy And Eva...mentioning
confidence: 99%
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