Examining the Interplay of Psychological Factors in Chronic Skin Disease: A Review on Depression, Anxiety, and Stress

Abstract

The genesis of chronic skin illnesses is intricately intertwined with genetics, the environment, psychological and the immune system. However, recent studies have shown that mental health issues can exacerbate and control the severity of chronic skin disorders. Focusing on illnesses including psoriasis, atopic dermatitis, and urticaria, this article seeks to evaluate and discuss the current literature on the interplay of psychological aspects in chronic skin diseases. Here, we investigate the two-way connection between emotional discomfort (such as stress, worry, or depression) and the physiology of various skin conditions. Furthermore, we address possible mechanisms underlying the link between mental health and skin diseases, which will help the physicians to select the medicines and treatment approach.