Examining the relationship between antihypertensive medication satisfaction and adherence in older patients

AlRuthia, Yazed; Hong, Song Hee; Graff, Carolyn; Kocak, Mehmet; Solomon, David; Nolly, Robert J.

doi:10.1016/j.sapharm.2016.06.013

Cited by 26 publications

(41 citation statements)

References 42 publications

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“…The included studies focussed on a wide range of disease areas including pulmonary diseases, osteoporosis, depression, cardiovascular diseases, Parkinson's disease, epilepsy, chronic kidney disease, cancer and diabetes mellitus . Two studies did not measure disease‐specific medication (non‐)adherence .…”

Section: Resultsmentioning

confidence: 99%

“…Two studies did not measure disease‐specific medication (non‐)adherence . Thirty‐six studies were specific to, or provided age stratified analysis for people aged ≥64 years, while the other 30 studies also included middle aged adults (≥50 years) . Thirteen authors of the included texts were contacted via e‐mail for further information, and 8 replied.…”

Section: Resultsmentioning

confidence: 99%

“…Thirteen authors of the included texts were contacted via e‐mail for further information, and 8 replied. In terms of adherence measurement, 54 studies measured medication (non‐)adherence using pharmacy claims data while 11 studies used self‐report methods, consisting of the 4‐item or 8‐item Morisky Medication Adherence Scale, or self‐reported PDC and MEMs was used in 4 studies …”

Section: Resultsmentioning

confidence: 99%

“…Overall, 48 studies were determined to be high quality, 17 were determined to be medium quality and 1 study was deemed to be low quality (Table S8). There was considerable variability with regards to external validity (generalisability), with 15 studies deemed medium quality and 11 studies achieving low quality . This was due to lack of detail on sampling or recruitment procedures or inclusion of specific populations only.…”

Section: Resultsmentioning

confidence: 99%

“…Overall, 48 studies were determined to be high quality, 4 and 11 studies achieving low quality. 24,46,50,52,53,56,69,70,[74][75][76] This was due to lack of detail on sampling or recruitment procedures or inclusion of specific populations only.…”

Section: Quality Assessmentmentioning

confidence: 99%

See 4 more Smart Citations

The association between medication non‐adherence and adverse health outcomes in ageing populations: A systematic review and meta‐analysis

Walsh

Cahir

Tecklenborg

et al. 2019

Brit J Clinical Pharma

148

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Aims The aim of this systematic review and meta‐analysis was to synthesise the evidence relating to medication non‐adherence and its association with health outcomes in people aged ≥50 years. Methods Seven databases were searched up to February 2019 for observational studies that measured medication (non‐)adherence as a predictor of the following health outcomes in adults aged ≥50 years: healthcare utilisation (hospitalisation, emergency department visits, outpatient visits and general practitioner visits), mortality, adverse clinical events and quality of life. Screening and quality assessment using validated criteria were completed by 2 reviewers independently. Random effects models were used to generate pooled estimates of association using adjusted study results. The full methodological approach was published on PROSPERO (ID: CRD42017077264). Results Sixty‐six studies were identified for qualitative synthesis, with 11 of these studies eligible for meta‐analyses. A meta‐analysis including 3 studies measuring medication non‐adherence in adults aged ≥55 years showed a significant association with all‐cause hospitalisation (adjusted odds ratio 1.17, 95% confidence interval [CI] 1.12, 1.21). A meta‐analysis including 2 studies showed that medication non‐adherence was not significantly associated with an emergency department visit (adjusted odds ratio 1.05, 95% CI 0.90, 1.22). Good adherence was associated with a 21% reduction in long‐term mortality risk in comparison to medication non‐adherence (adjusted hazard ratio 0.79, 95% CI 0.63, 0.98). Conclusion Medication non‐adherence may be significantly associated with all‐cause hospitalisation and mortality in older people. Medication adherence should be monitored and addressed in this cohort to minimise hospitalisation, improve clinical outcomes and reduce healthcare costs.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Quality Assessmentmentioning

confidence: 99%

See 3 more Smart Citations

The association between medication non‐adherence and adverse health outcomes in ageing populations: A systematic review and meta‐analysis

Walsh

Cahir

Tecklenborg

et al. 2019

Brit J Clinical Pharma

148

View full text Add to dashboard Cite

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Medication use problems among older adults at a primary care: A narrative of literature review

Christopher

Shrestha

et al. 2022

Aging Medicine

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The growing aging population is prominent globally. It is projected that by 2050, the proportion of the world's population over 60 years will be 22%. 1 This demographic transition to aging populations increases the health care burden because of multimorbidity and older adults' complex health care needs. Older adults often take several medications for chronic illnesses; however, the support ecosystem to optimize medication use in older adults is either lacking or not appropriately optimized, especially in the Organisation for Economic Co-operation and Development (OECD) regions. This region is compromised of 38 developed countries globally that aims to shape the policy constituting social, economic, and environmental challenges. 2 The aging process involves psychosocial and physiological changes that alter the body's pharmacokinetics and pharmacodynamics. 3 That leads to drug response variation and increases the

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Predictors of poor medication adherence of older people with hypertension

Wan

et al. 2022

Nursing Open

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Medication adherence is defined as the degree to which a patient's behaviour corresponds to the agreed recommendations from a medical staff member. Good medication adherence is critical for maintaining the health of people, especially for chronic diseases (Asche et al., 2011;Han et al., 2014). Hypertension is a global public health problem, and it is the most important risk factor for all-cause mortality and disability worldwide (Collaborators, 2016). In 2010, hypertension was considered as a major risk factor for the global burden of disease (Lim et al., 2012). Studies have shown that controlled blood pressure may reduce 50% of cardiovascular events compared to uncontrolled blood pressure in people with hypertension (Kohlman-Trigoboff, 2016); thus, hypertension is a major modifiable risk factor

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Examining the relationship between antihypertensive medication satisfaction and adherence in older patients

Cited by 26 publications

References 42 publications

The association between medication non‐adherence and adverse health outcomes in ageing populations: A systematic review and meta‐analysis

The association between medication non‐adherence and adverse health outcomes in ageing populations: A systematic review and meta‐analysis

Medication use problems among older adults at a primary care: A narrative of literature review

Predictors of poor medication adherence of older people with hypertension

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