Exanthematous Diseases of Childhood

Paller, Amy S.; Mancini, Anthony J.

doi:10.1016/b978-1-4377-0412-9.00016-2

Cited by 5 publications

(2 citation statements)

References 156 publications

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“…The presence of eruptions on the scalp is typical; oral cavity mucosa and other areas may also be involved. The eruptions are usually associated with pruritus, fever and malaise, although the severity of these symptoms varies among the affected individuals (6) . In immunosuppressed patients the diagnosis of varicella may be much more difficult.…”

Section: Discussionmentioning

confidence: 99%

Atypical course of varicella-zoster infection in a child with acute lymphoblastic leukaemia

Okarska‐Napierała¹,

Albrecht²,

Kawa³

et al. 2019

PEDIATR MED RODZ

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Varicella is a common, usually self-limiting, contagious childhood disease. Its clinical presentation in generally healthy children is characteristic enough to allow one to make a diagnosis; however, in immunosuppressed patients the diagnosis may be difficult due to atypical course of the disease. This article presents a diagnostically challenging case of a 5-year-old boy with newly diagnosed acute lymphoblastic leukaemia who developed varicella-zoster infection during induction steroid therapy, with an atypical, mild course without fever or pruritus, with eruptions of changed morphology. The presented case shows that in children with leukaemia who have been in contact with individuals with varicella, the occurrence of any rash should raise suspicion of the disease. In this group of patients the diagnostic method of choice is PCR test of skin eruption material. Intravenous acyclovir therapy should be started already before the PCR result comes back.

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Section: Discussionmentioning

confidence: 99%

Atypical course of varicella-zoster infection in a child with acute lymphoblastic leukaemia

Okarska‐Napierała¹,

Albrecht²,

Kawa³

et al. 2019

PEDIATR MED RODZ

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“…This means symptomatic relief of itching by using a drying agent such as a tanning agent or lotio alba/calamine lotion with antihistamines. In severe cases, especially in immunocompromised children, antiviral drugs such as acyclovir, alternative famciclovir, and valacyclovir may be used [ 44 ].…”

Section: Common Disorders In Children and Adolescents That Cause Itchingmentioning

confidence: 99%

Differential Diagnosis and Treatment of Itching in Children and Adolescents

Kang

Chung

et al. 2021

Biomedicines

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Itching is prevalent in children with skin disorders and associated with effects on their mood, quality of life, and social functioning. Surprisingly, there are no data on childhood prevalence of pruritus in the general population. The aim of this article is to explore the epidemiology, clinical manifestation, and treatment for itch (pruritus) in the pediatric population (from infancy to adolescence), and to be helpful to primary care physicians who assess and diagnose pediatric patients with itching. In this study, we searched for specific keywords using PubMed and MEDLINE (Ovid) and, then, refined the retrieved searches for each cause and treatment. As a result of reviewing the literature, atopic dermatitis was shown to be the most common cause of itching, especially during infancy and through preschool. Not only skin disorders but also systemic diseases, drugs, and postburn states can predispose an individual to itching in childhood. There are traditional and newly developed treatment modalities for itching in pediatric patients. However, because the pharmacokinetics and pharmacodynamics of childhood are different from those of adults, the medications for itching have to be applied carefully for these age groups. There are many areas to be elucidated regarding the prevalence and objective assessment of pruritus in pediatric patients. Moreover, the safety profiles of medications in the pediatric population need to be better understood. Further studies to investigate itching in childhood are warranted.

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