Excessive daytime sleepiness is associated with an increased frequency of falls and sarcopenia

Soysal, Pınar; Smıth, Lee; Tan, Semen Gökçe; Capar, Emre; Veronese, Nicola; Yang, Lin

doi:10.1016/j.exger.2021.111364

Cited by 26 publications

(18 citation statements)

References 43 publications

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“…Importantly, EDS is frequently observed in older adults, affecting approximately one-third of those aged 80 years or older [10]. Among older adults, EDS is associated with a higher fall risk [11,12], adiposity [13], metabolic syndrome [14], depressive disorders [15], and a lower hand-grip strength [16]. Moreover, daytime sleepiness has been reported to be associated with cardiovascular and overall mortality among older adults [17].…”

Section: Introductionmentioning

confidence: 99%

Associations between nutritional factors and excessive daytime sleepiness in older patients with chronic kidney disease

et al. 2021

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Section: Introductionmentioning

confidence: 99%

Associations between nutritional factors and excessive daytime sleepiness in older patients with chronic kidney disease

et al. 2021

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“…Actually, abnormal sleep durations are common health problems rather than simple behaviors among the middle-aged and older adults. For example, excessive daytime sleepiness (EDS) can cause falls, depression and cognitive impairment, and was estimated to occur in about 20% of the older people ( 51 ). A recent study investigated the association between malnutrition and excessive daytime sleepiness (EDS) in patients with and without dementia, and found that malnutrition, dysphagia, and vitamin D deficiency were significantly related to EDS ( 52 ).…”

Section: Discussionmentioning

confidence: 99%

Prospective association between sleep duration and cognitive impairment: Findings from the China Health and Retirement Longitudinal Study (CHARLS)

Liu

Wang

et al. 2022

Front. Med.

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ObjectiveThe association between sleep duration and cognition are inconclusive. Our study aimed to comprehensively investigate the effects of sleep duration on the risk of cognitive impairment in the middle-aged and older Chinese population.MethodsWe used the longitudinal cohort data from waves 1–4 (2011–2018) of the China Health and Retirement Longitudinal Study (CHARLS). Self-reported exposures included total sleep duration, nocturnal sleep duration, post-lunch napping, and changes in sleep duration over time according to face-to-face interviews. Cognitive function was assessed by a Chinese version of the Modified Mini-Mental State Examination (MMSE).ResultsA total of 7,342 eligible participants were included. The mean age was 61.5 ± 6.5 years, and 48.9% (3,588/7,342) were male. We identified a U-shaped association of total sleep duration as well as nocturnal sleep duration with the risk of cognitive impairment. People with 7–8 h of total sleep duration and 6–7 h of nocturnal sleep had the lowest risk of cognitive impairment. Further results showed that post-lunch napping within 2 h was beneficial to cognition and 60 min was optimal. Moreover, analyses of changes in sleep duration further supported that sleeping less or more was harmful to cognition. Notably, those “excessive-change” sleepers (from ≤6 to ≥9 h, or from ≥9 to ≤6 h) had more risks.ConclusionsKeeping 7–8 h per day was related to the lowest risk of cognitive impairment in midlife and late life, and an optimal post-lunch napping was 60 min for these stable sleepers. Especially, excessive changes in sleep duration over time led to poorer cognition. Our work highlights the importance of optimal sleep habits to cognitive function. The self-reported sleep measures limited our findings, and further studies are needed for verification.

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“…Excessive daytime sleepiness (EDS) becomes a chronic problem in 34% of stroke survivors and can significantly affect a stroke survivor’s daytime functional performance [ 33 ]. EDS can increase the frequency of falls through several different mechanisms [ 34 ]. For example, for healthy mobilisation and balance coordination, there must be effective integration of visual, vestibular, and proprioceptive senses [ 35 ].…”

Section: Discussionmentioning

confidence: 99%

The association between fatigue severity and risk of falls among middle-aged and older Australian stroke survivors

et al. 2022

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Background Fatigue is a common and often debilitating symptom experienced by many stroke survivors. Significant post stroke fatigue may predispose individuals to other health complications, such as falls, which can lead to fractures and soft tissue injuries. Only limited research has examined the association between fatigue and falls in stroke survivors. Methods Data were obtained from the Sax Institute’s 45 and Up Study, from a subset of individuals who had experienced a stroke. The Modified Fatigue Impact Scale—5-item version (MFIS-5) was used to measure the level of fatigue. A logistic regression model, adjusted for stroke characteristics and comorbidities, was used to determine the magnitude of association between change in fatigue score and odds of having had a fall. Results A total of 576 participants completed the questionnaire. A total of 214 (37.2%) participants reported having had a fall in the previous 12 months. There was a statistically significant association between fatigue scores and fall status (p < 0.001). Specifically, for every 1-point increase in the fatigue score (MFIS-5) (i.e. higher level of fatigue), the odds of a person having a fall is 1.10 times greater (AOR = 1.10; 95% CI 1.05, 1.15; p < 0.001). Conclusion This study revealed an association between an increasing risk of falls with increasing severity of post stroke fatigue. Accurate detection and management of fatigue may help reduce the risk of falls and should be the focus of future research.

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Excessive daytime sleepiness is associated with an increased frequency of falls and sarcopenia

Cited by 26 publications

References 43 publications

Associations between nutritional factors and excessive daytime sleepiness in older patients with chronic kidney disease

Associations between nutritional factors and excessive daytime sleepiness in older patients with chronic kidney disease

Prospective association between sleep duration and cognitive impairment: Findings from the China Health and Retirement Longitudinal Study (CHARLS)

The association between fatigue severity and risk of falls among middle-aged and older Australian stroke survivors

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