Excessive Fragmentary Myoclonus: What Do We Know?

Nepožitek, Jiří; Šonka, Karel

doi:10.14712/23362936.2017.1

Cited by 7 publications

(2 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The aetiology of FM remains unclear. The exact origin of the FM potentials is unknown, and the results of the existing studies are quite inconsistent so far (Nepozitek & Sonka, 2017). The remark that the appearance of the FM potentials resembles fasciculations (Frauscher et al, 2014;Montagna et al, 1988;Raccagni et al, 2016;Sonka et al, 2004) points to the possibility that the generator of FM could be located at the level of the spinal cord or peripheral nerves, and lence of electrophysiological abnormalities corresponding to polyneuropathy, root lesions and benign fasciculations in a group of patients with EFM (Raccagni et al, 2016).…”

Section: Discussionmentioning

confidence: 99%

Fragmentary myoclonus in idiopathic rapid eye movement sleep behaviour disorder

Nepožitek

Dostálová

Kemlink

et al. 2019

Journal of Sleep Research

View full text Add to dashboard Cite

Summary Fragmentary myoclonus is a result of muscle activity consisting of brief potentials in surface electromyography during polysomnography. Excessive fragmentary myoclonus is defined by increased intensity of the potentials. A few studies report excessive fragmentary myoclonus occurrence in neurodegenerative diseases. Because idiopathic rapid eye movement sleep behaviour disorder is considered as an early stage of neurodegeneration with involvement of the brainstem, we charted the prevalence and quantified the intensity of excessive fragmentary myoclonus in idiopathic rapid eye movement sleep behaviour disorder. Twenty‐nine patients (one woman, 28 men, mean age 68 years, SD 6.2) and 29 controls (two women, 27 men, mean age 65.6 years, SD 8.6) underwent polysomnography. Fragmentary myoclonus potentials were identified and counted according to internationally used criteria. Fragmentary myoclonus intensity was quantified by the fragmentary myoclonus index. Excessive fragmentary myoclonus was diagnosed in 75.9% (22 subjects) in idiopathic rapid eye movement sleep behaviour disorder, while in 34.5% (10 subjects) among the controls (p = 0.003). Quantitative analysis showed a wide‐range fragmentary myoclonus index in idiopathic rapid eye movement sleep behaviour disorder (4.0–632.4; median 60.7) and in the controls (0.8–938.1; median 34.3). The overall difference in fragmentary myoclonus index was not significant between the groups; however, patients with idiopathic rapid eye movement sleep behaviour disorder showed trends for higher fragmentary myoclonus index scores in wakefulness (p = 0.027), N1 (p = 0.032), N3 (p = 0.046) and R (p = 0.007). Fragmentary myoclonus index does not correlate with age, idiopathic rapid eye movement sleep behaviour disorder duration or R stage atonia deficiency. The prevalence of excessive fragmentary myoclonus is higher in idiopathic rapid eye movement sleep behaviour disorder compared with the controls, so fragmentary myoclonus should be taken into account in future research of rapid eye movement sleep behaviour disorder and motor control in sleep.

show abstract

Section: Discussionmentioning

confidence: 99%

Fragmentary myoclonus in idiopathic rapid eye movement sleep behaviour disorder

Nepožitek

Dostálová

Kemlink

et al. 2019

Journal of Sleep Research

View full text Add to dashboard Cite

show abstract

“…The possibility that EMF is a normal variant has not been ruled out. However, it can be associated with marked daytime sleepiness [98].…”

Section: Excessive Fragmentary Myoclonus (Efm)mentioning

confidence: 99%

The Parasomnias and Sleep Related Movement Disorders—A Look Back at Six Decades of Scientific Studies

Broughton

2022

CTN

View full text Add to dashboard Cite

The objective of this article is to provide a comprehensive personal survey of all the major parasomnias with coverage of their clinical presentation, investigation, physiopathogenesis and treatment. These include the four major members of the slow-wave sleep arousal parasomnias which are enuresis nocturna (bedwetting), somnambulism (sleepwalking), sleep terrors (pavor nocturnus in children, incubus attacks in adults) and confusional arousals (sleep drunkenness). Other parasomnias covered are sleep-related aggression, hypnagogic and hypnopompic terrifying hallucinations, REM sleep terrifying dreams, nocturnal anxiety attacks, sleep paralysis, sleep talking (somniloquy), sexsomnia, REM sleep behavior disorder (RBD), nocturnal paroxysmal dystonia, sleep starts (hypnic jerks), jactatio capitis nocturna (head and total body rocking), periodic limb movement disorder (PLMs), hypnagogic foot tremor, restless leg syndrome (Ekbom syndrome), exploding head syndrome, excessive fragmentary myoclonus, nocturnal cramps, and sleep-related epileptic seizures. There is interest in the possibility of relationships between sleep/wake states and creativity.

show abstract

Sleep-Related Movement Disorders: Hypnic Jerks

Whitney

Weiss

2018

Curr Sleep Medicine Rep

View full text Add to dashboard Cite

Excessive Fragmentary Myoclonus: What Do We Know?

Cited by 7 publications

References 23 publications

Fragmentary myoclonus in idiopathic rapid eye movement sleep behaviour disorder

Fragmentary myoclonus in idiopathic rapid eye movement sleep behaviour disorder

The Parasomnias and Sleep Related Movement Disorders—A Look Back at Six Decades of Scientific Studies

Sleep-Related Movement Disorders: Hypnic Jerks

Contact Info

Product

Resources

About