“…A further motivation of this procedure is to avoid the compensating errors caused by current non-evaluation fitting methods that utilize too few experimental data and/or too simplistic parameter changes, which may ultimately hinder modeling as a whole. Particularly, simplistic or arbitrary parameter adjustments in TALYS, tuned to provide a better fit for a singular reaction channel of interest, are non-unique and may not hold a global physical basis because neighbouring reaction channels can suffer from the fit choice [12,14,16,41,42,49,[59][60][61][62][63]. Nevertheless, these adjustment methods are representative of a norm in non-evaluation modeling work and can have real-world implications such as incorrect predicted yields during medical radioisotope production, high level coproduction of an unwanted contaminant, or poor particle transport calculations.…”