Exclusive Breast Milk vs. Hybrid Milk Feeding for Preterm Babies—A Randomized Controlled Trial Comparing Time to Full Feeds

Nandakumar, Anand; Pournami, Femitha; Prabhakar, Jyothi; Nair, P. M. C.; Jain, Naveen

doi:10.1093/tropej/fmz028

Cited by 3 publications

(3 citation statements)

References 20 publications

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“…Progressive enteral feeds were escalated (<1250 g increased at the rate of 20 mL/kg/d; >1250 g increased at the rate of 25 mL/kg/d) if there were no signs of feed intolerance, defined as at least 2 of the following: (1) abdominal distension > 2 cm at the level of umbilicus, (2) recurrent vomiting, (3) bilious/blood stained vomiting with systemic signs. If quantities of MOM were not available to reach daily feed targets, preterm formula (PreNan ® , Nestlé containing 79 kcal and 1.88 g of protein per 100 mL) was used, or PN was continued to reach targeted fluid intakes …”

Section: Methodsmentioning

confidence: 99%

“…This prospective study cohort included babies who participated in a published trial, conducted in the unit, that compared time to full feeds in preterms fed "mother's milk (MM) alone" vs "hybrid feed (HF)-MM supplemented with formula." 5 Parenteral nutrition. The unit's early optimal nutrition PN policy consists of written protocols for PN and its preparation under laminar hood, MEN, SFR, fluid and electrolyte management, and central line-care bundles.…”

Section: Study Cohort Aomentioning

confidence: 99%

“…If quantities of MOM were not available to reach daily feed targets, preterm formula (PreNan R , Nestlé containing 79 kcal and 1.88 g of protein per 100 mL) was used, or PN was continued to reach targeted fluid intakes. 5 Fortification. Bovine milk-based human-milk fortifier (Lactodex R human-milk fortifier: 1-g sachet in 25 mL of breast milk containing protein 0.27 g, energy 3.37 kcal, calcium 15.8 mg, and phosphorus 7.9 mg), oral calcium (total intake of 150-200 mg/kg/d), phosphorus (75-100 mg/kg/d), and vitamin D (400 IU/d) supplementation were done once the baby reached 150 mL/kg/d feeds and tolerated the same amount for at least 3 days.…”

Section: Study Cohort Aomentioning

confidence: 99%

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Outcome of Very Preterm Infants With Early Optimal Nutrition Strategy: A Comparative Cohort Study

et al. 2019

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Background Aggressive nutrition may benefit early growth; nevertheless, effects on neurodevelopmental outcomes are unclear. We planned a descriptive analytical study to compare survival without neurodevelopment disability (NDD) at 1 year in 2 groups during 2 time epochs—before and after implementation of early optimal nutrition strategies. NDD was defined as any one of the following: mental and/or motor development quotient < 85 at 12 months of age, corrected for prematurity; Denver Developmental Screening Test abnormal/suspect in even 1 domain out of the 4 domains; seizures; requirement of hearing aid; or blindness in 1 or both eyes. We also compared mortality, survival without bronchopulmonary dysplasia, necrotizing enterocolitis (NEC), retinopathy of prematurity (ROP), intraventricular hemorrhage, periventricular leukomalacia, sepsis, metabolic bone disease (MBD), and extrauterine growth restriction (EUGR). Methods Preterm neonates born between 27 and 32 weeks’ gestation were included. The prospective study group (AO) was recruited after implementation of early optimal nutrition policy. The comparative retrospective cohort (BO) received nutrition based on clinicians’ decisions. Both groups were followed up using a structured plan till 1 year corrected age. Results 137 neonates were enrolled in AO and 151 in the BO cohort. There was no statistically significant difference in survival without NDD at 1 year—75.5% in AO vs 72.1% in BO, odds ratio 0.84 (95% CI 0.5–1.6). Babies who received early optimal nutrition had less NEC, EUGR, and ROP requiring laser therapy but more MBD. Conclusion There was no difference in survival without NDD in early optimal nutrition cohort compared to the cohort before implementation of the nutrition strategy. Short‐term benefits themselves may justify the need for early optimal nutrition.

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Section: Methodsmentioning

confidence: 99%

Section: Study Cohort Aomentioning

confidence: 99%

Section: Study Cohort Aomentioning

confidence: 99%

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Outcome of Very Preterm Infants With Early Optimal Nutrition Strategy: A Comparative Cohort Study

et al. 2019

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Analysing cost of hospital care to a family with an extreme preterm neonate

Venkata

Pournami

Kumar

et al. 2020

Journal of Neonatal Nursing

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Por que amamentar?: Uma revisão de literatura

Caldas

Santos²,

Areia

et al. 2021

RSD

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O objetivo do estudo foi evidenciar os benefícios da amamentação para recém-nascidos prematuros. Trata-se de uma revisão integrativa da literatura, onde utilizou-se a Literatura Latino-Americana e do Caribe em Ciências da Saúde, Scientific Electronic Library Online e Medical Literature Analysis and Retrievel System Online, com os Descritores em Ciências da Saúde (DECS) “Amamentação AND Crescimento e Desenvolvimento AND Prematuro”. Após aplicação dos critérios de inclusão e exclusão, utilizou-se o protocolo PRISMA para elucidação da seleção e uma tabela para evidenciar os 13 estudos escolhidos para compor a revisão. O prematuro deve receber como primeira e se possível, única escolha, o leite materno, pois este é suficiente para as necessidades do bebê, possuindo ainda, várias qualidades imunológicas, que irão auxiliar no crescimento, desenvolvimento e na imaturidade, proporciona ainda, diversos benefícios para mãe e filho, atuando sobre a saúde física, biológica e mental, mas transparece dificuldades enfrentadas para poder usufruir desses benefícios, como a amamentação exclusiva não ser frequentemente alcançada. Conclui-se que a amamentação deve ser muito bem orientada e estimulada para a sua implementação, pois acarreta benefícios para a mãe e para o bebê, auxiliando na bem-estar e na saúde física e mental dos dois.

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Exclusive Breast Milk vs. Hybrid Milk Feeding for Preterm Babies—A Randomized Controlled Trial Comparing Time to Full Feeds

Cited by 3 publications

References 20 publications

Outcome of Very Preterm Infants With Early Optimal Nutrition Strategy: A Comparative Cohort Study

Outcome of Very Preterm Infants With Early Optimal Nutrition Strategy: A Comparative Cohort Study

Analysing cost of hospital care to a family with an extreme preterm neonate

Por que amamentar?: Uma revisão de literatura

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