Executive Function in Charge Syndrome

Understanding obstructive sleep apnea in children with CHARGE syndrome

“…Parents note that it is difficult to answer the questions in the behavioral and other symptom categories on the PSQ since typical CHARGE syndrome characteristics may be mistaken for OSA behavioral symptoms in these categories. For example, children with CHARGE syndrome have problems tracking their behavior in terms of task attainment and have problems controlling impulses, following social rules and focusing on activities [27]. These behaviors lead to confusion on the behavioral subscale of the PSQ.…”

Executive Functioning in Children, Adolescents, and Young Adults with Chronic Kidney Disease

“…1 These executive function abilities are essential for countless aspects of daily life such as learning, academic skills, social competence, and overall adaptive behaviors. Notably, executive dysfunction has been documented in a wide variety of clinical populations, including patients with traumatic brain injury, 1,2 CHARGE syndrome, 3 central nervous system disorders, 4 Spina Bifida, 5,6 Nephropathic Cystanosis, 7 Muscular Dystrophy, 8 Epilepsy, 9,10 liver transplants, 11 Multiple Sclerosis, 12 Neurofibromatosis, 13 and Chronic Kidney Disease (CKD). [14][15][16][17][18][19][20][21][22][23][24][25] Executive Function in CKD There is a growing literature documenting a wide range of cognitive impairments associated with CKD, with the functions of attention, memory, verbal memory and language, processing speed, and executive function all having been identified as problematic in CKD in children [14][15][16][17]23 and adults, [18][19][20][21][22]24,25 especially with worsening disease severity.…”

The education of learners with CHARGE syndrome

“…Executive function concerns a set of higher cognitive processes that enable us to control and regulate our cognitive actions and engage in goal‐directed behaviour. Previous research (for example, Hartshorne et al, ) suggests that executive dysfunction may be present in a significant number of learners with CHARGE. The data from this study were compared with a summary of the complex skills involved with executive function (Cooper‐Kahn & Dietzel, ).…”

“…Difficulty in developing social and emotional skills is well documented for individuals with CHARGE (for example, Hartshorne et al, ). Within this study 37 (71%) of the cohort were perceived to have difficulty expressing their emotional state.…”