Executive function in teen and adult women: Association with maternal status and early adversity

Almanza-Sepúlveda, Mayra Linné; Chico, Elsie; González, Andrea; Hall, Geoffrey B.; Steiner, Meir; Fleming, Alison S.

doi:10.1002/dev.21766

Cited by 12 publications

(5 citation statements)

References 68 publications

(124 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Comparadas con adolescentes que no han sido madres, las madres adolescentes tienen mayores dificultades en la memoria de trabajo (Almanza-Sepúlveda et al, 2018a;Chico et al, 2014), y si bien la maternidad parece conferirles un efecto moderador de la atención a las segundas con respecto a las primeras (Almanza-Sepúlveda et al, 2018a), cuando se les compara enero-junio 2022 | ISSN 2594-1852 17-48 con madres adultas, presentan menor calidad en esta atención y una pobre memoria de trabajo (Almanza-Sepúlveda et al, 2018a;Chico et al, 2014).…”

Section: Madres Adolescentes: Sensibilidad Materna Y Funciones Ejecut...unclassified

“…Las interacciones saludables entre la madre y el bebé son fundamentales para el desarrollo físico, cognitivo y psicológico de este (Feldman, 2011;Smith et al, 2006;Swingler et al, 2017). Varios estudios han buscado determinar la asociación entre las funciones ejecutivas y la maternidad adolescente (Almanza-Sepúlveda et al, 2018a;Chico et al, 2014;Giardino et al, 2008;Krpan et al, 2005). En general estos estudios muestran que, comparadas con madres adultas, tienen menor control de la atención y menor memoria de trabajo, lo cual se ha asociado con respuestas menos sensibles hacia sus bebés.…”

Section: Introductionunclassified

See 1 more Smart Citation

Madres adolescentes, Sensibilidad materna y funciones ejecutivas

Almanza-Sepúlveda¹

2022

punto

Self Cite

View full text Add to dashboard Cite

En esta revisión se estudiará la maternidad adolescente, su asociación con la conducta maternal adulta y sus funciones ejecutivas. Este trabajo con el objetivo de reconocer los conceptos que comprenden la maternidad adolescente. Las funciones ejecutivas aún están madurando durante la adolescencia, por lo que, en comparación con las madres adultas, las madres adolescentes muestran menor sensibilidad materna. En esta revisión se presta especial atención a los procesos de cuidado y de memoria de trabajo, ya que son funciones ejecutivas determinantes de la conducta maternal que han sido poco estudiadas en madres adolescentes.

show abstract

Section: Madres Adolescentes: Sensibilidad Materna Y Funciones Ejecut...unclassified

Section: Introductionunclassified

Madres adolescentes, Sensibilidad materna y funciones ejecutivas

Almanza-Sepúlveda¹

2022

punto

Self Cite

View full text Add to dashboard Cite

show abstract

“…Finally, and not surprisingly, optimal mothering and its psychological profile are affected by mothers' early and other life experiences and their effects can be transmitted to the next generation of mothers. 56,[74][75][76] Looking to the animal work and to human studies, and by understanding the phenomenology of mothering and its neurochemistry and neurobiology, we are in a good position to choose candidate genes. We look both to the animal work on the role of gene expression and gene products on maternal and associated behaviors, especially in rodents but extending up to nonhuman primates and humans.…”

Section: Postpartum Depression and Maternal Behavior: Psychological Ementioning

confidence: 99%

“…Finally, and not surprisingly, optimal mothering and its psychological profile are affected by mothers’ early and other life experiences and their effects can be transmitted to the next generation of mothers. 56,74 –76…”

Section: Levels Of Analysismentioning

confidence: 99%

Molecular and Genetic Bases of Mammalian Maternal Behavior

Fleming

Kraemer

2019

Gender and the Genome

Self Cite

View full text Add to dashboard Cite

New mammalian mothers undergo an increase in their maternal responsiveness with the birth of their infants. Associated with changes in responsiveness are how attracted mothers are to infant cues, mothers' affective state, and their cognitive and executive function. In comparison to nonmothers, new mothers are more attracted to infant odors and are more easily alerted to their vocalizations; they undergo a reduction in withdrawal behaviors and anxiety, but increased lability. Their maternal sensitivity (human or licking intensity, rat) is associated with higher levels of attention and working memory. Maternal responsiveness and these associated behaviors are associated with large shifts in maternal hormones across parturition. Changes in expression of neuropeptides and neurotransmitters are affected by mothers' prior experiences, including their very early experiences in their families of origin. The present review describes the regulation of mothering and associated behaviors by the neurotransmitters, oxytocin, dopamine, and serotonin, in a rat model and in humans. Emphasis is then given to studies that focus on the role of genes and what we know about their expression in the functioning of these 3 neurochemical systems in new mothers. Studies of early experience, genetics, and human mothering show gene-by-environment interplays (interactions) for a number of DNA singlenucleotide polymorphism within both the oxytocin and serotonin systems, where associations between mothers' early experiences and mothering/affect depend on mothers' genotype. Studies also show associations between different dopamine genes and many aspects of both mothering and maternal affect. Where known, we also discuss evidence that the relation between early experience and mothering is often an indirect one, mediated through an effect of experience on mothers' affect or executive function. In many cases, mothers' genetic profile moderates these relations. Finally, preliminary evidence suggests a role of epigenetic mechanisms in these processes.

show abstract

“…Pregnancy history is associated, however, with mixed findings on cognition in middle age, and conflicting data may be due to both the type of cognition tested and pregnancy history characteristics such as amount of parity and age of first pregnancy (Colucci et al, 2006;Cui et al, 2014;Gatewood et al, 2005;Jang et al, 2018;Puri et al, 2023). Earlier ages of first pregnancy show less beneficial effects on cognition and increased dementia risk later in life compared to later ages of first pregnancy (Almanza-Sepulveda et al, 2018;Chico et al, 2014;Fu et al, 2023;Gong et al, 2022;Rocca et al, 1991). Although there is clear evidence pregnancy leaves long-term signatures on the brain and on behavior, pregnancy characteristics, such as the age of first pregnancy, remain largely understudied.…”

Section: Introductionmentioning

confidence: 99%

Pregnancy History and Estradiol Influence Spatial Memory, Hippocampal Plasticity, and Inflammation in Middle-aged Rats

Puri,

Lieblich,

Ibrahim

et al. 2024

Preprint

View full text Add to dashboard Cite

Pregnancy and motherhood (parity) can have long-term effects on cognition and brain aging in both humans and rodents. Estrogens are related to cognitive function and neuroplasticity. Estrogens can improve cognition in postmenopausal women, but the evidence is mixed, in part due to differences in hormone therapy dose and composition. In addition, past pregnancy influences brain aging and cognition, with earlier age of first pregnancy being associated with poorer outcomes with aging. However, few studies have examined specific features of pregnancy history such as the age of first pregnancy or the possible mechanisms underlying these changes. We examined whether maternal age at first pregnancy and estradiol treatment differentially affected hippocampal neuroplasticity, inflammation, activation, and cognition in middle-age. Thirteen-month-old rats (who were nulliparous (never mothered) or previously primiparous (had a litter) at 3 months or 7 months) received daily injections of estradiol (or sesame oil vehicle) for sixteen days and were tested on the Morris Water Maze. An older age of first pregnancy was associated with impaired spatial memory but improved performance on reversal training, and increased new neurons in the ventral hippocampus compared to the other groups. Estradiol decreased total activation and percent activation of new neurons in the dorsal hippocampus, regardless of parity history. Estradiol also decreased the production of anti-inflammatory cytokines based on age of first pregnancy. This work suggests that estradiol affects neuroplasticity and neuroinflammation in middle age, and that pregnancy history can have long lasting effects on hippocampus structure and function.

show abstract

Executive function in teen and adult women: Association with maternal status and early adversity

Cited by 12 publications

References 68 publications

Madres adolescentes, Sensibilidad materna y funciones ejecutivas

Madres adolescentes, Sensibilidad materna y funciones ejecutivas

Molecular and Genetic Bases of Mammalian Maternal Behavior

Pregnancy History and Estradiol Influence Spatial Memory, Hippocampal Plasticity, and Inflammation in Middle-aged Rats

Contact Info

Product

Resources

About