Executive Functions and P300 Latency in Elderly Depressed Patients and Control Subjects

Kindermann, Sandra S.; Kalayam, Balu; Brown, Gregory G.; Burdick, Katherine E.; Alexopoulos, George S.

doi:10.1097/00019442-200002000-00008

Cited by 50 publications

(30 citation statements)

References 35 publications

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“…Besides, they also illustrated that 'total (percentage) errors' score was useful to assist in the interpretation of WC-PE results. 18 Karakas et al 26 and Karzmark 31 stated that 'percentage of conceptual level responses', perseveration and executive functions were related with working memory. Therefore, as is mentioned in the previous part, these five test scores described above were chosen to compare the differences between control and BD group.…”

Section: Discussionmentioning

confidence: 99%

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Executive dysfunctions and depression in Behçet’s disease without explicit neurological involvement

Erberk-Özen¹,

Bırol

Boratav³

et al. 2006

Psychiatry Clin Neurosci

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This study aims to assess the executive functions and depression status in patients with Behçet's disease without explicit neurological involvement and to evaluate cognitive functions in this group of patients independent of accompanying depression. In the present study, 30 patients with Behçet's disease in the non-active phase of their illness and 30 healthy volunteers were included. In the evaluation of depression levels, Beck Depression Inventory was employed. The executive functions of the patients were evaluated by Wisconsin Card Sorting Test (WCST) and Stroop Test (ST). Beck Depression Inventory scores measured in the Behçet's disease group, in which no clinically serious depression was observed, were higher than the control group. Then, it was observed that the scores of neuropsychological tests of the Behçet's disease group were found to be significantly lower, especially in WCST, while significant relations were revealed between Beck Depression Inventory scores and WCST, ST scores. The authors' findings suggest that there may be factors other than depression causing executive impairment in patients with Behçet's disease without explicit neurological symptoms. Executive dysfunctions may occur in association with mild depressive states due to chronic disease stress or silent and/or future neurological involvement of Behçet's disease, especially in the frontal lobes.

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Section: Discussionmentioning

confidence: 99%

“…18 Neuroimaging and NPT studies together provide further evidence for functional impairment in DLPFC in depression. 12,19 Degl'Innocenti et al .…”

Section: Introductionmentioning

confidence: 93%

Executive dysfunctions and depression in Behçet’s disease without explicit neurological involvement

Erberk-Özen¹,

Bırol

Boratav³

et al. 2006

Psychiatry Clin Neurosci

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“…23 Long latency for the P300 wave was associated with executive impairment. 24 Moreover, long P300 latency is found in subcortical disorders. 25 …”

Section: Discussionmentioning

confidence: 99%

Prefrontal Dysfunction and Treatment Response in Geriatric Depression

Kalayam

Alexopoulos²

1999

Arch Gen Psychiatry

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245

178

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“…Poor concentration is a common symptom of depression. Moreover, nondemented depressed elders may present with disturbances in processing speed and executive functioning [ 21,22 ] . To evaluate the etiology of cognitive dif fi culties in late-life depression, a thorough neuropsychological examination is strongly recommended.…”

Section: Cognitive De Fi Cits Associated With Depressionmentioning

confidence: 99%

Assessment of Depression and Anxiety in Older Adults

Kiosses

2012

Handbook on the Neuropsychology of Aging and Dementia

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Late-life depression and anxiety may contribute to detrimental consequences for patients and their families. They impair functioning, negatively affect quality of life, disrupt interpersonal relationships and increase utilization of medical services. Further, late-life depression is associated with increased morbidity, mortality and is the most common psychiatric diagnosis in attempted or completed suicides. This chapter explores diagnostic considerations and provides clinical pearls for the accurate assessment of the most common depression and anxiety disorders in older adults.

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Executive Functions and P300 Latency in Elderly Depressed Patients and Control Subjects

Cited by 50 publications

References 35 publications

Executive dysfunctions and depression in Behçet’s disease without explicit neurological involvement

Executive dysfunctions and depression in Behçet’s disease without explicit neurological involvement

Prefrontal Dysfunction and Treatment Response in Geriatric Depression

Assessment of Depression and Anxiety in Older Adults

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