Exercise and Rehabilitation for Individuals with Multiple Sclerosis

Brown, Theodore R.; Kraft, George H.

doi:10.1016/j.pmr.2005.01.005

Cited by 97 publications

(98 citation statements)

References 151 publications

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“…Importantly, analysis of HRQoL data revealed the following: significant benefits of the exercise program for the Physical Dimension summary subscale of the Sickness Impact Profile; transiently significant benefits in the Social Interaction and Emotional Behavior subscales of the Sickness Impact Profile; a positive correlation between gains in aerobic capacity and improvements in the Tension, Vigor, Fatigue and Confusion subscales of the Profile of Mood States; and no significant changes for either group in FSS. The positive results of this trial stimulated excitement about the potential for rehabilitation for MS [17] and helped to further allay fears of exercise-induced exacerbations. The present study lends further credence to the idea that exercise training can improve QoL in those with MS.…”

Section: Discussionmentioning

confidence: 92%

“…Change in quality of life measures and Expanded Disability Status Scale (EDSS) from baseline to end of study for participants with multiple sclerosis who received BWSTT alone followed by BWSTT with robotic assistance (T-R) versus BWSTT with robotic assistance followed by BWSTT alone (R-T). Until the end of the twentieth century, exercise was widely believed to exacerbate symptoms of MS, triggering relapses and thus hastening the progression of the disease [17]. As a result, people with MS were cautioned to avoid exercise and excessive expenditures of energy in activities of daily living [34].…”

Section: Discussionmentioning

confidence: 99%

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Effect of robot-assisted versus conventional body-weight-supported treadmill training on quality of life for people with multiple sclerosis

Wier¹,

Hatcher²,

Triche³

et al. 2011

JRRD

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Abstract-This study describes the effect of body-weightsupported treadmill training (BWSTT) on quality of life (QoL) for multiple sclerosis (MS) patients. Thirteen individuals with MS and gait impairment randomly received two blocks of six biweekly training sessions: (1) robot-assisted BWSTT then BWSTT alone (R-T) or (2) BWSTT alone then robot-assisted BWSTT (T-R). No statistically significant differences were found between robot-assisted BWSTT and unassisted BWSTT for improving QoL outcome measures. The change in Physical Component Summary scores from baseline to the end of the 12 training sessions improved significantly more in the R-T than the T-R group. Within-participant longitudinal changes in QoL for all participants from both groups combined showed significant improvements in 5 of the 13 QoL measures. The results of this pilot study suggest that both types of BWSTT may improve QoL for people with gait dysfunction secondary to MS. Clinical Trial Registration: ClinicalTrials.Gov, NCT00156676, "Restoration of Walking in Multiple Sclerosis Using Treadmill Training"; http://www.clinicaltrials.gov/.

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Section: Discussionmentioning

confidence: 92%

Section: Discussionmentioning

confidence: 99%

Effect of robot-assisted versus conventional body-weight-supported treadmill training on quality of life for people with multiple sclerosis

Wier¹,

Hatcher²,

Triche³

et al. 2011

JRRD

View full text Add to dashboard Cite

show abstract

“…Historically, exercise was discouraged for people with MS for fear of possibly increasing fatigue or triggering a disease exacerbation. 1 However, the beneficial role of exercise in individuals with MS is becoming clear. For example, Rietberg et al 2 found strong evidence of improved muscle strength, activity tolerance, and mobility in nine high-quality randomized controlled trials investigating the effects of exercise therapy for MS.…”

mentioning

confidence: 99%

Aerobic Exercise in People with Multiple Sclerosis

Swank¹,

Thompson²,

Medley³

2013

International Journal of MS Care

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The aims of this study were to explore the feasibility of structured aerobic exercise followed by a period of unstructured physical activity and determine the impact of such exercise on cognition, mood, and quality of life in people with multiple sclerosis (MS). A convenience sample of 9 individuals with relapsing-remitting MS performed 30 minutes of aerobic exercise (upper-and lower-extremity ergometry and treadmill ambulation) twice weekly for

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“…15 The inclusion criteria were age 18 to 64 years, ability to ambulate without the assistance of another person for to these and other factors. 2,3 This variation in signs and symptoms makes planning rehabilitation programs challenging. People with MS are responsive to exercise interventions, 4 although programs that focus on a single modality (eg, strength training) may not have a broad effect on the wide range of impairments and disabilities that may result from MS.…”

Section: Participantsmentioning

confidence: 99%

Feasibility and Impact of an 8-Week Integrative Yoga Program in People with Moderate Multiple Sclerosis–Related Disability

Cohen¹,

Kietrys²,

Fogerite³

et al. 2017

International Journal of MS Care

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Background: This pilot study determined the feasibility of a specifically designed 8-week yoga program for people with moderate multiple sclerosis (MS)-related disability. We explored the program's effect on quality of life (QOL) and physical and mental performance. Methods:We used a single-group design with repeated measurements at baseline, postintervention, and 8-week follow-up. Feasibility was examined through cost, recruitment, retention, attendance, and safety. Maximizing physical function and quality of life (QOL) is of paramount importance for the person with multiple sclerosis (MS). Disease progression, severity, and signs and symptoms are unpredictable and vary between people. 1 People with MS may experience fatigue, asthenia, balance and mobility loss, depression, and decreased cognitive function. 2 The QOL is impaired in individuals with MS owing International Journal of MS Care 31Yoga for MS vention models. In general, yoga activities vary widely between types and between instructors within types. More importantly, there is a lack of programs tailored to the needs of people with MS that are scalable to accommodate differing levels and types of disability. Recognizing this limitation, we created a standardized, integrative yoga program for people with moderate MS-related disability through a modified Delphi process. 13 Delphi panel participants included people with MS, certified yoga instructors with experience teaching people with MS, and health-care professionals and researchers with experience and expertise in MS care or yoga. This resulted in a comprehensive program specifically designed to address the needs of people with moderate MS-related disability. Details of this process have been presented elsewhere. 14 The program was designed with scalable difficulty to meet the heterogeneous capabilities of a sample of people with moderate MS-related disability while maximizing program standardization. The first objective of this study was to examine the feasibility of the specifically designed yoga program in people with moderate MS-related disability. The second objective was to examine the immediate and lasting effects of the program on function, activity, and participation. Methods DesignWe conducted a single-group pilot study, approved by the Rutgers University-Newark institutional review board, to assess the safety, feasibility, and effects of a specifically designed yoga program on QOL, physical performance, and mental performance in people with moderate MS-related disability. Repeated measures were obtained at three time points: baseline, after 8 weeks of yoga classes (postintervention), and again 8 weeks later (follow-up). Weekly home practice tracking forms were completed throughout the study.

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Exercise and Rehabilitation for Individuals with Multiple Sclerosis

Cited by 97 publications

References 151 publications

Effect of robot-assisted versus conventional body-weight-supported treadmill training on quality of life for people with multiple sclerosis

Effect of robot-assisted versus conventional body-weight-supported treadmill training on quality of life for people with multiple sclerosis

Aerobic Exercise in People with Multiple Sclerosis

Feasibility and Impact of an 8-Week Integrative Yoga Program in People with Moderate Multiple Sclerosis–Related Disability

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