Plant-based diets have emerged as athletic performance enhancers for various types of exercise. Therefore, the present study evaluated the effectiveness of plant-based diets on aerobic and strength/power performances, as well as on body mass index (BMI) of physically active individuals. This systematic review and meta-analysis was conducted and reported according to the guidelines outlined in the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) statement. A systematic search of electronic databases, including PubMed, Web of Science and SPORTDiscus, was performed. On the basis of the search and inclusion criteria, four and six studies evaluating the effects of plant-based diets on aerobic and strength/power performances in humans were respectively included in the systematic review and meta-analysis. Plant-based diets had a moderate but positive effect on aerobic performance (0.55; 95% CI: 0.29 to 0.81), and no effect on strength/power performance (-0.30; 95% CI: -0.67 to 0.07). The altogether analyses of both aerobic and strength/power exercises revealed that athletic performance was unchanged (0.01; 95% CI: -0.21 to 0.22) in athletes that adopted plant-based diets. However, a small negative effect on BMI (-0.27; 95% CI: -0.40 to –0.15) was induced by these diets. The results indicate that plant-based diets have the potential to exclusively assist aerobic performance. On the other hand, these diets do not jeopardize strength/power performance. Overall, the predicted effects of plant-based diets on physical performance are impactless, even though the BMI of their adherents is reduced.