Exercise haemodynamics of coarctation of the aorta: Acute effects of propranold

Abstract

Eight patients with aortic coarctation were studied at rest and during supine bicycle exercise before and after intravenous propranolol O0r7 mg./kg. The accentuated pressor response to exercise in patients with coarctation may be due to the mechanical effect of an increase in the rate of left ventricular ejection into an aorta with a limited run-off capacity. As the rate of left ventricular ejection may be reduced by beta-adrenergic inhibition (Cumming and Carr, I967), the exercise haemodynamics of coarctation of the aorta were restudied after the intravenous administration of propranolol. PatientsData on the patients are given in Table I. Case 7 was a woman, the others were men or boys. The mean age was 14 years and the mean work load on

Long-Term Results of Balloon Angioplasty for Native Coarctation of the Aorta in the Surgical Specialty Teaching Hospital/Cardiac Center/Hawler

“…Also elastic properties of the normal aorta decrease with distance from the aortic root. In COA of aorta, the proximal aortic segment is characterized by an increase in collagen and a decrease in smooth muscle [11].…”