Exercise hemodynamics of bovine versus porcine bioprostheses: A prospective randomized comparison of the mosaic and perimount aortic valves

Eichinger, Walter; Botzenhardt, Florian; Keithahn, Alexandra; Guenzinger, Ralf; Bleiziffer, Sabine; Wagner, Ina; Bauernschmitt, Robert; Lange, Rüediger

doi:10.1016/j.jtcvs.2004.08.028

Cited by 57 publications

(37 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…7,11,12,32,33 As described in other studies, the bovine prostheses appear to be superior concerning pressure gradient and effective orifice areas. 1,8,14,24 In this study, the Magna as well as the Soprano showed a clear tendency toward lower pressure gradients and larger EOAs throughout all annulus size groups when compared with porcine prostheses.…”

Section: Mean Pressure Gradientsmentioning

confidence: 48%

“…Prior comparisons of bovine and porcine heart valves showed a superiority of bovine tissue prostheses, especially in small annulus sizes. 14,24 Those studies only compared 2 different valves, whereas this study includes 2 bovine and 3 porcine prostheses and might help to stress the findings in those prior studies.…”

Section: S142 Circulation September 15 2009mentioning

confidence: 96%

“…1,8,14,18,19 In the present study, we focus on aortic bioprostheses designed for and implanted in a complete supraannular position. The design of a complete supraannular heart valve prosthesis aims to optimize the area available for the bloodstream through the aortic root orifice.…”

Section: S142 Circulation September 15 2009mentioning

confidence: 99%

“…Pressure gradients of the Magna, the Mosaic, and the Soprano are in accord with findings of other groups. 1,[3][4][5][6]8,13,14,20,22,[25][26][27][28][29][30][31] There are preliminary in vivo hemodynamic data available regarding the Mosaic Ultra 10 and only 1 in vivo evaluation of the Epic, which was published previously by our group. 4 The in vitro data concerning hemodynamic gradients of the Epic and the Ultra correspond well with our results.…”

Section: Mean Pressure Gradientsmentioning

confidence: 99%

“…Therefore, we use as a basis for comparisons-as in previous studies-the patient's aortic annulus, which is measured with a standardized sizer during surgery. 1,4,8,13,14 …”

mentioning

confidence: 99%

See 4 more Smart Citations

The Complete Supraannular Concept

et al. 2009

Self Cite

View full text Add to dashboard Cite

Background— Complete supraannular placement of an aortic bioprosthesis is one approach to optimize the hemodynamic result of an aortic valve replacement. It is achieved with the combination of a special valve design and the supraannular sewing technique with noneverted mattress sutures. We evaluated 5 bioprostheses designed for complete supraannular placement to assess potential hemodynamic differences caused by factors (eg, valve material) other than implantation position. Methods and Results— In 336 patients (mean age, 72.0±7.1 years; 143 women), hemodynamics including mean pressure gradients, effective orifice areas, and indices and incidence of patient-prosthesis mismatch were evaluated 6 months after surgery. Annulus diameter was measured during surgery. Patients received the Carpentier Edwards Perimount Magna (Magna, n=169), the Medtronic Mosaic (Mosaic, n=46), the Mosaic Ultra (Ultra, n=17), the SJM Epic Supra (Epic, n=46), and the Sorin Soprano (Soprano, n=58). For small annulus sizes (<23 mm), the mean pressure gradients of the Magna (11.82±4.8 mm Hg) were significantly lower than the Mosaic (16.04±6.1 mm Hg) and the Ultra (22.0±4.1 mm Hg), and the Soprano (13.3±5.2 mm Hg) was hemodynamically superior to the Ultra. For medium (23 to 24 mm) and large (>24 mm) annulus sizes, the mean pressure gradients of the Magna were lower than the Epic (10.0±3.5 mm Hg versus 14.9±6.4 mm Hg; 9.9±4.0 mm Hg versus 18.6±12.7 mm Hg). Furthermore, in patients with large annulus size, the mean pressure gradients of the Soprano (11.4±3.8 mm Hg) were lower compared with the Epic (18.5±12.7 mm Hg). Severe patient-prosthesis mismatch was observed more frequently in patients with the Mosaic (12/46; 26.1%) and the Ultra (3/17; 17.6%) prostheses. Conclusions— Complete supraannular placement cannot prevent high pressure gradients or patient-prosthesis mismatch thoroughly, but the choice of a bovine prosthesis can optimize hemodynamic performance.

show abstract

Section: Mean Pressure Gradientsmentioning

confidence: 48%

Section: S142 Circulation September 15 2009mentioning

confidence: 96%

Section: S142 Circulation September 15 2009mentioning

confidence: 99%

Section: Mean Pressure Gradientsmentioning

confidence: 99%

“…Therefore, we use as a basis for comparisons-as in previous studies-the patient's aortic annulus, which is measured with a standardized sizer during surgery. 1,4,8,13,14 …”

mentioning

confidence: 99%

See 3 more Smart Citations

The Complete Supraannular Concept

et al. 2009

Self Cite

View full text Add to dashboard Cite

show abstract

Stented Bioprosthetic Valves

Santarpino

Raja

2020

Cardiac Surgery

View full text Add to dashboard Cite

Heart valve replacement: Which valve for which patient?

Huh

Bakaeen²

2006

Curr Cardiol Rep

View full text Add to dashboard Cite

The ideal heart valve substitute would show no deterioration or thrombogenicity, offer no resistance to blood flow, and be easy to implant. However, such a valve does not exist and we must accept compromises in some of these qualities based on our patients' needs. In selection of cardiac valve prosthesis, valve-related factors such as durability, thrombogenicity, and fluid dynamics should be carefully matched to patient-related factors such as age, size, life expectancy, comorbidities, plans for pregnancy, and lifestyle. In addition, surgeon- or operation-related factors should be considered. Technical aspects of implantation, ease of reoperation, and operative mortalities may tip the risk and benefit balance in a particular direction. We review currently available heart valve prostheses and the clinical factors that are involved in selection of a heart valve substitute.

show abstract

Exercise hemodynamics of bovine versus porcine bioprostheses: A prospective randomized comparison of the mosaic and perimount aortic valves

Abstract: Our data show a significant superiority of pressure gradients for the bovine bioprosthesis, especially with small valve sizes, when compared with the porcine device, which is more distinctive during exercise.

Cited by 57 publications

References 21 publications

The Complete Supraannular Concept

The Complete Supraannular Concept

Stented Bioprosthetic Valves

Heart valve replacement: Which valve for which patient?

Contact Info

Product

Resources

About