Exercise-Induced Post-Ischemic Left Ventricular Delayed Relaxation or Diastolic Stunning

Ishii, Katsuhisa; Imai, Makoto; Suyama, Tamaki; Maenaka, Motoyoshi; Nagai, Takahiro; Kawanami, Masaki; Seino, Yutaka

doi:10.1016/j.jacc.2008.09.057

Cited by 109 publications

(75 citation statements)

References 35 publications

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“…Delayed LV relaxation detected by radial strain from apical views (transverse strain) during the first third of diastole 5 and 10 minutes after exercise ("diastolic stunning") identified significant coronary stenosis with a sensitivity of 97% and specificity of 93%. 35 These encouraging data suggest that quantitative strain data are sensitive and provide incremental diagnostic information in DSE.…”

Section: Dobutamine Stress For Detection Of Coronary Artery Diseasementioning

confidence: 92%

Strain and Strain Rate Echocardiography and Coronary Artery Disease

Hoit

2011

Circ: Cardiovascular Imaging

182

130

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Section: Dobutamine Stress For Detection Of Coronary Artery Diseasementioning

confidence: 92%

Strain and Strain Rate Echocardiography and Coronary Artery Disease

Hoit

2011

Circ: Cardiovascular Imaging

182

130

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“…Recently, the strain imaging diastolic index (SI-DI) derived from transverse SI was demonstrated to be a sensitive marker to detect postischemic regional LV delayed relaxation or diastolic stunning, even after complete systolic functional recovery during stress echocardiography in CAD patients. 11) Furthermore, SI-DI was reported to be reduced even 24 hours after an ischemic event. 12) Similarly, using cardiac single-photon emission tomography with β-methyl-p-[…”

mentioning

confidence: 99%

Prediction of Coronary Artery Stenosis at Rest in Patients With Normal Left Ventricular Wall Motion

et al. 2013

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SummaryNoninvasive detection of coronary artery stenosis usually requires a stress test in patients without left ventricular (LV) regional wall motion abnormalities (RWMA). In contrast, abnormal regional LV relaxation caused by ischemia may persist beyond recovery from transient ischemia. The aim of the present study was to determine whether segmental analysis of abnormal regional LV relaxation using the strain imaging diastolic index (SI-DI) at rest could predict coronary artery stenosis in the three major vessels in patients without LV dysfunction or RWMA. We performed 2D speckle tracking echocardiography and coronary angiography in 85 patients without RWMA with suspected coronary artery disease. Patients with LV dysfunction or acute coronary syndrome were excluded. Echocardiographic images of the LV were obtained in the apical 2-, 3-, and 4-chamber views and divided into 6 segments. In each segment, SI-DI derived from transverse strain imaging was determined. Forty-eight patients had significant coronary artery stenosis (≥ 70%). The optimal cutoff values of SI-DI were 60.5% in the mid anteroseptal segment for detecting left anterior descending artery stenosis (sensitivity, 83.3%; specificity, 81.1%), 60.5% in the basal anterolateral segment for detecting left circumflex artery stenosis (sensitivity, 80.9%; specificity, 90.3%), and 61.5% in the basal inferior segment for detecting right coronary artery stenosis (sensitivity, 74.1%; specificity, 77.8%). A segmental analysis of SI-DI at rest predicted coronary artery stenosis in the three major vessels in patients without RWMA. This noninvasive method may be useful for detecting coronary artery stenosis without a stress test. (Int Heart J 2013; 54: 266-272)

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“…For instance, tardokynesis has been completely characterized by strain in ischemic conditions [39]. In other studies from of our center [40,41] we have observed that torsion is diminished in patients with ischemia during exercise testing.…”

Section: Ischemia In Non-cadmentioning

confidence: 76%